FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992331280> ?p ?o ?g. }

• W1992331280 endingPage "592" @default.
• W1992331280 startingPage "584" @default.
• W1992331280 abstract "BackgroundThere is an association between adiposity and asthma prevalence, but the relationship to asthma control is unclear.ObjectivesWe sought to understand the relationships among adiposity, sex, and asthma control in inner-city adolescents with asthma.MethodsWe prospectively followed 368 adolescents with moderate-to-severe asthma (ages 12-20 years) living in 10 urban areas for 1 year. Asthma symptoms and exacerbations were recorded, and pulmonary function and exhaled nitric oxide levels were measured every 6 weeks. Adiposity measures (body mass index [BMI] and dual-energy X-ray absorptiometric scans) were made, and blood was collected for measurement of allergy markers, adiponectin, leptin, TNF-α, IL-6, and C-reactive protein levels.ResultsMore than 60% of female subjects and 50% of male subjects were above the 85th percentile of BMI for age. Higher BMI was associated with more symptom days (R = 0.18, P = .02) and exacerbations (R = 0.18, P = .06) among female subjects only. Adiponectin was inversely related to asthma symptoms (R = −0.18, P < .05) and exacerbations (R = −0.20, P < .05) and positively with FEV1/forced vital capacity ratio (R = 0.15, P < .05) in male subjects only independent of body size. There was no relationship between adiposity or adipokines and total IgE levels, blood eosinophil counts, and exhaled nitric oxide levels. Dual-energy X-ray absorptiometry provided little additional value in relating adiposity to asthma outcome in this population of adolescents.ConclusionAdiposity is associated with poorer asthma control in female subjects. Adiponectin is associated with improved asthma control in male subjects. There is an association between adiposity and asthma prevalence, but the relationship to asthma control is unclear. We sought to understand the relationships among adiposity, sex, and asthma control in inner-city adolescents with asthma. We prospectively followed 368 adolescents with moderate-to-severe asthma (ages 12-20 years) living in 10 urban areas for 1 year. Asthma symptoms and exacerbations were recorded, and pulmonary function and exhaled nitric oxide levels were measured every 6 weeks. Adiposity measures (body mass index [BMI] and dual-energy X-ray absorptiometric scans) were made, and blood was collected for measurement of allergy markers, adiponectin, leptin, TNF-α, IL-6, and C-reactive protein levels. More than 60% of female subjects and 50% of male subjects were above the 85th percentile of BMI for age. Higher BMI was associated with more symptom days (R = 0.18, P = .02) and exacerbations (R = 0.18, P = .06) among female subjects only. Adiponectin was inversely related to asthma symptoms (R = −0.18, P < .05) and exacerbations (R = −0.20, P < .05) and positively with FEV1/forced vital capacity ratio (R = 0.15, P < .05) in male subjects only independent of body size. There was no relationship between adiposity or adipokines and total IgE levels, blood eosinophil counts, and exhaled nitric oxide levels. Dual-energy X-ray absorptiometry provided little additional value in relating adiposity to asthma outcome in this population of adolescents. Adiposity is associated with poorer asthma control in female subjects. Adiponectin is associated with improved asthma control in male subjects." @default.
• W1992331280 created "2016-06-24" @default.
• W1992331280 creator A5001991232 @default.
• W1992331280 creator A5002714937 @default.
• W1992331280 creator A5012934813 @default.
• W1992331280 creator A5026189939 @default.
• W1992331280 creator A5026846286 @default.
• W1992331280 creator A5033765434 @default.
• W1992331280 creator A5043173147 @default.
• W1992331280 creator A5053044434 @default.
• W1992331280 creator A5062167940 @default.
• W1992331280 creator A5063976675 @default.
• W1992331280 creator A5064437485 @default.
• W1992331280 creator A5072488545 @default.
• W1992331280 creator A5075140875 @default.
• W1992331280 creator A5077572213 @default.
• W1992331280 creator A5080742079 @default.
• W1992331280 date "2010-03-01" @default.
• W1992331280 modified "2023-10-02" @default.
• W1992331280 title "Asthma control, adiposity, and adipokines among inner-city adolescents" @default.
• W1992331280 cites W1964164121 @default.
• W1992331280 cites W1965943690 @default.
• W1992331280 cites W1967942432 @default.
• W1992331280 cites W1970274008 @default.
• W1992331280 cites W1971566616 @default.
• W1992331280 cites W1972421380 @default.
• W1992331280 cites W1973019664 @default.
• W1992331280 cites W1979764360 @default.
• W1992331280 cites W1981261500 @default.
• W1992331280 cites W1982208958 @default.
• W1992331280 cites W1994997234 @default.
• W1992331280 cites W2000884457 @default.
• W1992331280 cites W2008824306 @default.
• W1992331280 cites W2008869160 @default.
• W1992331280 cites W2013926834 @default.
• W1992331280 cites W2015493089 @default.
• W1992331280 cites W2025438762 @default.
• W1992331280 cites W2025800033 @default.
• W1992331280 cites W2028435922 @default.
• W1992331280 cites W2029349706 @default.
• W1992331280 cites W2034804696 @default.
• W1992331280 cites W2035763164 @default.
• W1992331280 cites W2038562158 @default.
• W1992331280 cites W2039942234 @default.
• W1992331280 cites W2054821151 @default.
• W1992331280 cites W2058669590 @default.
• W1992331280 cites W2061376514 @default.
• W1992331280 cites W2073412359 @default.
• W1992331280 cites W2076633494 @default.
• W1992331280 cites W2079271825 @default.
• W1992331280 cites W2079284592 @default.
• W1992331280 cites W2086075876 @default.
• W1992331280 cites W2092509345 @default.
• W1992331280 cites W2099034063 @default.
• W1992331280 cites W2099398527 @default.
• W1992331280 cites W2100457204 @default.
• W1992331280 cites W2103070907 @default.
• W1992331280 cites W2106397535 @default.
• W1992331280 cites W2108940923 @default.
• W1992331280 cites W2109849857 @default.
• W1992331280 cites W2112693061 @default.
• W1992331280 cites W2117760446 @default.
• W1992331280 cites W2120270144 @default.
• W1992331280 cites W2121813141 @default.
• W1992331280 cites W2125930781 @default.
• W1992331280 cites W2128879211 @default.
• W1992331280 cites W2130427463 @default.
• W1992331280 cites W2138750223 @default.
• W1992331280 cites W2138839361 @default.
• W1992331280 cites W2141677989 @default.
• W1992331280 cites W2142302739 @default.
• W1992331280 cites W2147991740 @default.
• W1992331280 cites W2148672185 @default.
• W1992331280 cites W2149411747 @default.
• W1992331280 cites W2159211110 @default.
• W1992331280 cites W2160103886 @default.
• W1992331280 cites W2160548369 @default.
• W1992331280 cites W2163819694 @default.
• W1992331280 cites W2164749658 @default.
• W1992331280 cites W2165302519 @default.
• W1992331280 cites W2166370133 @default.
• W1992331280 cites W2167521510 @default.
• W1992331280 cites W2170095916 @default.
• W1992331280 cites W2170184153 @default.
• W1992331280 cites W2604596332 @default.
• W1992331280 cites W2971947803 @default.
• W1992331280 cites W4211006694 @default.
• W1992331280 cites W4249727000 @default.
• W1992331280 cites W4377077046 @default.
• W1992331280 doi "https://doi.org/10.1016/j.jaci.2010.01.053" @default.
• W1992331280 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3596816" @default.
• W1992331280 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20226295" @default.
• W1992331280 hasPublicationYear "2010" @default.
• W1992331280 type Work @default.
• W1992331280 sameAs 1992331280 @default.
• W1992331280 citedByCount "163" @default.
• W1992331280 countsByYear W19923312802012 @default.
• W1992331280 countsByYear W19923312802013 @default.

• next