FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992337136> ?p ?o ?g. }

• W1992337136 endingPage "18" @default.
• W1992337136 startingPage "11" @default.
• W1992337136 abstract "The convulsant action of 3-mercaptopropionic acid (3-MPA), a known inhibitor of glutamate decarboxylase activity, was studied in 7-, 12-, 18- and 25-day-old rats and in adult animals. 3-MPA elicited predominantly clonic, minimal seizures as well as generalized tonic-clonic (major) seizures at all developmental stages studied. The CD50 for major seizures did not change during development; CD50 for minimal seizures was significantly lower in 18-day-old rats than in older animals. Latency to the onset of seizures was shortest in 18-day-old rats and extremely long in 12- and, especially, in 7-day-old rats. This long latency might signify either changing molecular properties of glutamate decarboxylase during development or slow turnover of GABA at early postnatal stages. Electrocorticographic recordings demonstrated sharp EEG components in the frontal region as a first sign of 3-MPA action, and seizure patterns exhibited similar developmental changes as found with other seizure models (a decrease in duration of individual graphoelements and an increase in synchronization among various cortical regions). This indicates the primary importance of brain maturation in the expression of epileptic EEG phenomena. The correlation between EEG and motor phenomena was poor in the youngest animals and it ameliorated with age, but it never became perfectly coincidental." @default.
• W1992337136 created "2016-06-24" @default.
• W1992337136 creator A5022942557 @default.
• W1992337136 creator A5034308073 @default.
• W1992337136 creator A5034699859 @default.
• W1992337136 creator A5053469261 @default.
• W1992337136 creator A5056400712 @default.
• W1992337136 creator A5082608220 @default.
• W1992337136 date "1993-09-01" @default.
• W1992337136 modified "2023-10-05" @default.
• W1992337136 title "Motor and electrocorticographic epileptic activity induced by 3-mercaptopropionic acid in immature rats" @default.
• W1992337136 cites W1152299788 @default.
• W1992337136 cites W144114650 @default.
• W1992337136 cites W1491577159 @default.
• W1992337136 cites W1494944546 @default.
• W1992337136 cites W1966027216 @default.
• W1992337136 cites W1978867898 @default.
• W1992337136 cites W1980062692 @default.
• W1992337136 cites W1983107337 @default.
• W1992337136 cites W1988674256 @default.
• W1992337136 cites W2001688550 @default.
• W1992337136 cites W2013744939 @default.
• W1992337136 cites W2015832128 @default.
• W1992337136 cites W2018090586 @default.
• W1992337136 cites W2019483700 @default.
• W1992337136 cites W2027742741 @default.
• W1992337136 cites W2038525234 @default.
• W1992337136 cites W2045705953 @default.
• W1992337136 cites W2047852076 @default.
• W1992337136 cites W2055423501 @default.
• W1992337136 cites W2059485890 @default.
• W1992337136 cites W2059887873 @default.
• W1992337136 cites W2077458988 @default.
• W1992337136 cites W2077645502 @default.
• W1992337136 cites W2091395882 @default.
• W1992337136 cites W2091859039 @default.
• W1992337136 cites W2143133343 @default.
• W1992337136 cites W2332641532 @default.
• W1992337136 cites W2398815392 @default.
• W1992337136 cites W2406226951 @default.
• W1992337136 cites W2416008477 @default.
• W1992337136 cites W283985012 @default.
• W1992337136 doi "https://doi.org/10.1016/0920-1211(93)90034-5" @default.
• W1992337136 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8243436" @default.
• W1992337136 hasPublicationYear "1993" @default.
• W1992337136 type Work @default.
• W1992337136 sameAs 1992337136 @default.
• W1992337136 citedByCount "26" @default.
• W1992337136 countsByYear W19923371362014 @default.
• W1992337136 countsByYear W19923371362017 @default.
• W1992337136 countsByYear W19923371362020 @default.
• W1992337136 crossrefType "journal-article" @default.
• W1992337136 hasAuthorship W1992337136A5022942557 @default.
• W1992337136 hasAuthorship W1992337136A5034308073 @default.
• W1992337136 hasAuthorship W1992337136A5034699859 @default.
• W1992337136 hasAuthorship W1992337136A5053469261 @default.
• W1992337136 hasAuthorship W1992337136A5056400712 @default.
• W1992337136 hasAuthorship W1992337136A5082608220 @default.
• W1992337136 hasConcept C119599485 @default.
• W1992337136 hasConcept C126322002 @default.
• W1992337136 hasConcept C127413603 @default.
• W1992337136 hasConcept C127573956 @default.
• W1992337136 hasConcept C134018914 @default.
• W1992337136 hasConcept C15744967 @default.
• W1992337136 hasConcept C169760540 @default.
• W1992337136 hasConcept C170493617 @default.
• W1992337136 hasConcept C181199279 @default.
• W1992337136 hasConcept C185592680 @default.
• W1992337136 hasConcept C2778186239 @default.
• W1992337136 hasConcept C2778900099 @default.
• W1992337136 hasConcept C522805319 @default.
• W1992337136 hasConcept C55493867 @default.
• W1992337136 hasConcept C61174792 @default.
• W1992337136 hasConcept C71924100 @default.
• W1992337136 hasConcept C82876162 @default.
• W1992337136 hasConcept C9497952 @default.
• W1992337136 hasConceptScore W1992337136C119599485 @default.
• W1992337136 hasConceptScore W1992337136C126322002 @default.
• W1992337136 hasConceptScore W1992337136C127413603 @default.
• W1992337136 hasConceptScore W1992337136C127573956 @default.
• W1992337136 hasConceptScore W1992337136C134018914 @default.
• W1992337136 hasConceptScore W1992337136C15744967 @default.
• W1992337136 hasConceptScore W1992337136C169760540 @default.
• W1992337136 hasConceptScore W1992337136C170493617 @default.
• W1992337136 hasConceptScore W1992337136C181199279 @default.
• W1992337136 hasConceptScore W1992337136C185592680 @default.
• W1992337136 hasConceptScore W1992337136C2778186239 @default.
• W1992337136 hasConceptScore W1992337136C2778900099 @default.
• W1992337136 hasConceptScore W1992337136C522805319 @default.
• W1992337136 hasConceptScore W1992337136C55493867 @default.
• W1992337136 hasConceptScore W1992337136C61174792 @default.
• W1992337136 hasConceptScore W1992337136C71924100 @default.
• W1992337136 hasConceptScore W1992337136C82876162 @default.
• W1992337136 hasConceptScore W1992337136C9497952 @default.
• W1992337136 hasIssue "1" @default.
• W1992337136 hasLocation W19923371361 @default.
• W1992337136 hasLocation W19923371362 @default.
• W1992337136 hasOpenAccess W1992337136 @default.

• next