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• W1992337762 abstract "Data supporting epidemiological transition from a predominant burden of infectious diseases to one of chronic diseases in Africa result mostly from hospital surveys. To estimate the cardiovascular disease (CVD) burden in Gabon. The study was conducted in Ntoum (8765 inhabitants). All subjects aged greater or equal to 40 years were invited to participate. Participants were interviewed about CVD history and risk factors; they responded to questionnaires on claudication and angina and had a clinical examination, including lower limb pulse palpation and bilateral brachial pressure measurement. Subjects were considered to have CVD in case of history of CVD (coronary artery, cerebrovascular and peripheral arterial diseases), a positive questionnaire or an abnormal finding during clinical examination. The study included 736 subjects (313 men; 423 women). Systolic hypertension was highly prevalent (up to 47.7% and 53.7% in men and women aged 50 to 60 years, respectively). Of the 382 patients with hypertension, 74 (19.4%) were treated and only 22 (5.8%) were considered to have controlled hypertension. Overall, CVD was identified in 98 (13.3%) cases. Overall and newly diagnosed CVD prevalence rates were 14.7% and 11.5% for men and 14.9% and 8.9% for women, respectively. The presence of CVD was associated with hypertension (hazard ratio [HR] 3.69, 95% confidence interval [CI] 2.21–6.16; P < 0.0001). Hypertension was predictive of stroke (HR 4.57, 95% CI 1.26–16.50; P < 0.05), peripheral artery disease (HR 2.03, 95% CI 1.03–4.00; P < 0.05) and subclavian artery stenosis (HR 5.79, 95% CI 2.21–15.2; P < 0.05). Our findings provide strong evidence of ongoing epidemiological transition in Gabon, where CVD prevalence rates increase mainly with hypertension, affecting about one in six individuals aged over 40 years. L’objectif de cette étude est de préciser la prévalence des affections cardiovasculaires symptomatiques et asymptomatiques en population générale au Gabon. L’enquête, effectuée dans la région de Ntoum (8765 habitants), a inclus tous les sujets supérieurs ou égaux à 40 ans ; elle comportait la recherche des antécédents et facteurs de risque cardiovasculaire, l’administration de questionnaires pour l’angor et la claudication, un examen clinique avec une prise de pression artérielle aux deux bras et la palpation des pouls des membres inférieurs. Les sujets ont été considérés comme présentant une affection cardiovasculaire en cas d’antécédent de coronaropathie, cérébrovasculaire, d’artériopathie des membres inférieurs, devant un questionnaire positif ou d’anomalie lors de l’examen clinique. La population était de 736 sujets (313 hommes, 423 femmes). La prévalence de l’hypertension artérielle était élevée (entre 50 à 60 ans, 47,7 % pour les hommes et 53,7 % pour les femmes). Parmi les 382 patients hypertendus, 74 (19,4 %) étaient traités et 22 (5,8 %) controlés. La prévalence d’une affection cardiovasculaire était de 13,3 % (98 sujets) ; pour les hommes et les femmes, elle s’élevait respectivement à 14,7 % et 11,5 %, et à 11,5 % et 8,9 % pour les nouvellement identifiées. L’hypertension augmentait le risque général (HR 3,69, IC 95 % 2,21–6,16 ; p < 0,001), celui d’accident vasculaire cérébral (HR 4,57, IC 95 % 1,26–16,50 ; p < 0,05), d’artériopathie des membres (HR 2,03, IC 95 % 1,03–4,00 ; p < 0,05) et de sténose subclavière (HR 5,79, IC 95 % 2,21–15,2 ; p < 0,05). Ces données suggèrent une transition épidémiologique au Gabon. L’hypertension semble un important problème de santé publique dans ce pays." @default.
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• W1992337762 date "2012-02-01" @default.
• W1992337762 modified "2023-09-27" @default.
• W1992337762 title "Prevalence of cardiovascular disease in Gabon: A population study" @default.
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• W1992337762 doi "https://doi.org/10.1016/j.acvd.2011.12.005" @default.
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