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- W1992353900 endingPage "745" @default.
- W1992353900 startingPage "733" @default.
- W1992353900 abstract "Stem cells have the unique properties of self-renewal, pluripotency and a high proliferative capability, which contributes to a large biomass potential. Hence, these cells act as a useful source for acquiring renewable adult cell lines. This, in turn, acts as a potent therapeutic tool to treat various diseases related to the heart, liver and kidney, as well as neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. However, a major problem that must be overcome before it can be effectively implemented into the clinical setting is a suitable delivery system that can retain an optimal quantity of the cells at the targeted site for a maximal clinical benefit; a system that will give a mechanical as well as an immune protection to the foreign cells, while at the same time enhancing the yields of differentiated cells, maintaining cell microenvironments and sustaining the differentiated cell functions. To address this issue we opted for a novel delivery system, termed the ‘artificial cells’, which are semipermeable microcapsules with strong and thin multilayer membrane components with specific mass transport properties. Here, we briefly introduce the concept of artificial cells for encapsulation of stem cells and investigate the application of microencapsulation technology as an ideal tool for all stem transplantations and relate their role to the emerging field of cellular cardiomyoplasty." @default.
- W1992353900 created "2016-06-24" @default.
- W1992353900 creator A5011645957 @default.
- W1992353900 creator A5026041461 @default.
- W1992353900 creator A5031206155 @default.
- W1992353900 creator A5036032663 @default.
- W1992353900 date "2009-09-01" @default.
- W1992353900 modified "2023-09-26" @default.
- W1992353900 title "Microencapsulated stem cells for tissue repairing: implications in cell-based myocardial therapy" @default.
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- W1992353900 doi "https://doi.org/10.2217/rme.09.43" @default.
- W1992353900 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19761398" @default.