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- W1992368170 abstract "Mixed-backbone oligonucleotides containing alternative phosphorothioate and phosphodiester linkages in the 2′-O-methylribonucleosides segment show increased affinity with complementary targets, increased stability towards nucleases in vitro and in vivo, and reduced phosphorothioate-related prolongation of partial thromboplastin time compared to phosphorothioate oligodeoxynucleotides, thereby providing antisense agents with reduced side effects." @default.
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- W1992368170 title "Mixed-Backbone oligonucleotides as second-generation antisense agents with reduced phosphorothioate-related side effects" @default.
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- W1992368170 doi "https://doi.org/10.1016/s0960-894x(98)00591-5" @default.
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