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• W1992382893 abstract "Recently, there is a tendency to expand tumour sizes qualifying for OLT. The present study re-evaluates tumour size and histopathological features as selection criteria for OLT.Retrospective analysis of 93 adult HCC patients underwent OLT between June 1985 and December 2003. Median follow-up was 28 months (1-222 months). The Milan criteria were routinely applied since 1994.Five year survival rate of HCC patients was significantly lower than in patients transplanted for benign diseases, 41 and 71%, respectively (p<0.0001). Multivariate analysis revealed that the presence of vascular invasion represents the most significant predictor (p<0.001) affecting the survival rate. Survival was also significantly impaired when the tumour size was >5 cm (p<0.05), whereas the number of nodules had no significant effect on survival. Consequently, the survival rate for HCC fulfilling the Milan criteria histologically improved to 70% since 1994.Tumour size has been shown to be the most important pre-operatively detectable predictor for patient survival after OLT." @default.
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• W1992382893 date "2005-11-01" @default.
• W1992382893 modified "2023-10-18" @default.
• W1992382893 title "Tumour size is an important predictor for the outcome after liver transplantation for hepatocellular carcinoma" @default.
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• W1992382893 doi "https://doi.org/10.1016/j.ejso.2005.06.003" @default.
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