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• W1992498903 abstract "We have measured the rate of transfer of unesterified cholesterol from rat erythrocyte to triolein emulsions modeling nascent triglyceride-rich lipoproteins. Emulsions (mean diameter ≈ 130 nm) were prepared with low cholesterol content (less than 2%) and various phosphatidylcholines that resulted in fluid (egg yolk phosphatidylcholine, dimyristoyl phosphatidylcholine) at transition (dipalmitoyl phosphatidylcholine) and solid (distearoyl phosphatidylcholine) surfaces at 37° C. Emulsions were incubated for 0, 20, 60, and 180 min with rat erythrocytes. Incubation mixtures initially contained approximately equal masses of phospholipid in the emulsion surfaces and the outer layer of plasma membrane of rat erythrocytes. There was a gradual and significant increase (P < 0.05) in the percent mass of unesterified cholesterol and consequently unesterified cholesterol to phospholipid molar ratio in the surface phase of three reisolated emulsions with time: dimyristoyl phosphatidylcholine-low cholesterol- > > egg yolk phosphatidylcholine-low cholesterol- > dipalmitoyl phosphatidylcholine-low cholesterol-triolein. There was no significant change in the composition of the surface phase of distearoyl phosphatidylcholine-low cholesterol-triolein emulsions. Therefore, transfer of unesterified cholesterol to the surface phase of emulsions during incubation with intact rat erythrocytes at 37° C in the absence of transfer proteins and plasma proteins is attributable to the degree of surface fluidity of emulsions." @default.
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• W1992498903 date "1993-11-01" @default.
• W1992498903 modified "2023-10-17" @default.
• W1992498903 title "The rate of transfer of unesterified cholesterol from rat erythrocytes to emulsions modeling nascent triglyceride-rich lipoproteins and chylomicrons depends on the degree of fluidity of the surface" @default.
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• W1992498903 doi "https://doi.org/10.1016/0955-2863(93)90034-t" @default.
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