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• W1992545780 abstract "We report a potential synthetic route to the isoprostanes and the neuroprostanes that could allow ready access to each of the enantiomerically pure diastereomers of the several regioisomers of these important human metabolites. The key transformation in the synthesis is a highly diastereoselective thermal intramolecular ene reaction. A critical observation is that the four enantiomerically pure diastereomers of an intermediate acetylenic ester are easily separated from one another. Each of these four has been carried on to a different enantiomerically pure diastereomer of 13-F4t-neuroprostane." @default.
• W1992545780 created "2016-06-24" @default.
• W1992545780 creator A5022717028 @default.
• W1992545780 creator A5059031550 @default.
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• W1992545780 date "2008-03-15" @default.
• W1992545780 modified "2023-09-24" @default.
• W1992545780 title "A Potential Route to Neuroprostanes and Isoprostanes: Preparation of the Four Enantiomerically Pure Diastereomers of 13-F_4t-NeuroP" @default.
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• W1992545780 doi "https://doi.org/10.1021/jo702600v" @default.
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