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- W1992581815 abstract "Synaptosomal associated protein of 25 kDa (SNAP-25) has been implicated in the membrane fusion machinery of neurotransmitter release and axonal growth. Using immunocytochemistry, we have analyzed the distribution and ultrastructural localization of SNAP-25 in selected areas of the central and peripheral nervous systems of adult rats. We show that the protein is specifically expressed in the trans face of the Golgi apparatus and in the axonal compartment. In axons and nerve endings, SNAP-25 is localized to discrete areas of the membranes of most organelles such as the axoplasmic reticulum, the axolemma, the outer membrane of mitochondria and synaptic vesicles. This wide distribution of SNAP-25 suggests that the protein is involved in the fusion of membranes in the whole axonal compartment of neurons. © 1995 Wiley-Liss, Inc." @default.
- W1992581815 created "2016-06-24" @default.
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- W1992581815 date "1995-05-22" @default.
- W1992581815 modified "2023-10-09" @default.
- W1992581815 title "Ultrastructural localization of SNAP-25 within the rat spinal cord and peripheral nervous system" @default.
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- W1992581815 doi "https://doi.org/10.1002/cne.903560111" @default.
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