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• W1992620103 abstract "Neurons are generated from stem or progenitor cells in discrete areas in the adult brain. The exact temporal and spatial distribution of adult neurogenesis has, however, been difficult to establish because of inherent limitations with the currently used techniques, and there are numerous controversies with regard to whether neurons are generated in specific regions or in response to insults. We describe here the generation of transgenic mice that express conditionally active Cre recombinase under the control of a nestin enhancer element. These mice allow the recombination of reporter alleles specifically in neural stem and progenitor cells and the visualization of their progeny in the adult brain. This offers a simple and efficient way to visualize live adult born neurons without the caveats of currently used techniques." @default.
• W1992620103 created "2016-06-24" @default.
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• W1992620103 date "2006-09-01" @default.
• W1992620103 modified "2023-10-16" @default.
• W1992620103 title "Genetic visualization of neurogenesis" @default.
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• W1992620103 doi "https://doi.org/10.1016/j.yexcr.2006.05.012" @default.
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