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- W1992621808 abstract "The metabolic syndrome (MetS), characterized by obesity, hyperlipidemia, hypertension, and insulin resistance, is a growing epidemic worldwide, requiring new prevention strategies and therapeutics. The concept of prebiotics refers to selective stimulation of growth and/or activity(ies) of one or a limited number of microbial genus(era)/species in the gut microbiota that confer(s) health benefits to the host. Sequencing the gut microbiome and performing metagenomics has provided new knowledge of the significance of the composition and activity of the gut microbiota in metabolic disease. As knowledge of how a healthy gut microbiota is composed and which bacterial metabolites are beneficial increases, tailor-made dietary interventions using prebiotic fibers could be developed for individuals with MetS. In this review, we describe how dietary fibers alter short-chain fatty acid (SCFA) profiles and the intrinsic and extrinsic effects of prebiotics on host metabolism. We focus on several key aspects in prebiotic research in relation to MetS and provide mechanistic data that support the use of prebiotic fibers in order to alter the gut microbiota composition and SCFA profiles. Further studies in the field should provide reliable mechanistic and clinical evidence for how prebiotics can be used to alleviate MetS and its complications. Additionally, it will be important to clarify the effect of individual differences in the gut microbiome on responsiveness to prebiotic interventions." @default.
- W1992621808 created "2016-06-24" @default.
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- W1992621808 date "2014-05-01" @default.
- W1992621808 modified "2023-10-18" @default.
- W1992621808 title "Designing future prebiotic fiber to target metabolic syndrome" @default.
- W1992621808 cites W1596984217 @default.
- W1992621808 cites W1811610985 @default.
- W1992621808 cites W1877854700 @default.
- W1992621808 cites W1893825827 @default.
- W1992621808 cites W1934624334 @default.
- W1992621808 cites W1934661217 @default.
- W1992621808 cites W1953635918 @default.
- W1992621808 cites W1972920113 @default.
- W1992621808 cites W1986440965 @default.
- W1992621808 cites W1993127959 @default.
- W1992621808 cites W2006831212 @default.
- W1992621808 cites W2013164470 @default.
- W1992621808 cites W2014805679 @default.
- W1992621808 cites W2018409805 @default.
- W1992621808 cites W2019791774 @default.
- W1992621808 cites W2023615726 @default.
- W1992621808 cites W2025222862 @default.
- W1992621808 cites W2027040468 @default.
- W1992621808 cites W2029726557 @default.
- W1992621808 cites W2041059386 @default.
- W1992621808 cites W2042025821 @default.
- W1992621808 cites W2042074642 @default.
- W1992621808 cites W2051860376 @default.
- W1992621808 cites W2071841602 @default.
- W1992621808 cites W2073332363 @default.
- W1992621808 cites W2080056378 @default.
- W1992621808 cites W2082056357 @default.
- W1992621808 cites W2083119809 @default.
- W1992621808 cites W2085175109 @default.
- W1992621808 cites W2086487313 @default.
- W1992621808 cites W2087292184 @default.
- W1992621808 cites W2091771078 @default.
- W1992621808 cites W2094479438 @default.
- W1992621808 cites W2097714259 @default.
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- W1992621808 cites W2123429605 @default.
- W1992621808 cites W2123769352 @default.
- W1992621808 cites W2124149838 @default.
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- W1992621808 doi "https://doi.org/10.1016/j.nut.2013.08.013" @default.
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