Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992623361> ?p ?o ?g. }
- W1992623361 endingPage "2201" @default.
- W1992623361 startingPage "2191" @default.
- W1992623361 abstract "The aim of this work was to determine whether mitral valve (MV) annuloplasty benefits patients with moderate/severe (3+/4+) functional ischemic mitral regurgitation (MR) who undergo coronary artery bypass grafting (CABG). Mitral regurgitation is a strong predictor of poor outcomes in patients with ischemic cardiomyopathy; whether correcting it at the time of CABG improves outcomes is less certain. From 1991 to 2003, 390 patients with 3+/4+ ischemic MR had CABG with (n = 290) or without (n = 100) MV annuloplasty. Groups were propensity-matched using demographics, extent of coronary disease, regional wall motion, and quantitative electrocardiography. Survival, echocardiographic severity of MR, and New York Heart Association (NYHA) functional class were compared. One-, 5-, and 10-year survival was 88%, 75%, and 47% after CABG alone and 92%, 74%, and 39% after CABG + MV annuloplasty (p = 0.6). Mortality was increased in patients with severe lateral wall motion abnormalities (p = 0.05), ST-segment elevation in lateral leads (p < 0.004), and higher QRS voltage sum (p < 0.0001). Patients undergoing CABG alone were more likely to have 3+/4+ postoperative MR than those undergoing CABG + MV annuloplasty (48% vs. 12% at 1 year, p < 0.0001). The NYHA functional class substantially improved in both groups (p < 0.001) and remained improved; at 5 years, 23% of patients having CABG + mitral annuloplasty and 25% having CABG alone were in NYHA functional class III/IV. Although CABG + MV annuloplasty reduces postoperative MR and improves early symptoms compared with CABG alone, it does not improve long-term functional status or survival in patients with severe functional ischemic MR. The MV annuloplasty in this setting, without addressing fundamental ventricular pathology, is insufficient to improve long-term clinical outcomes." @default.
- W1992623361 created "2016-06-24" @default.
- W1992623361 creator A5003737429 @default.
- W1992623361 creator A5011317354 @default.
- W1992623361 creator A5024406367 @default.
- W1992623361 creator A5034718335 @default.
- W1992623361 creator A5048979901 @default.
- W1992623361 creator A5059484584 @default.
- W1992623361 creator A5065932248 @default.
- W1992623361 creator A5073592687 @default.
- W1992623361 date "2007-06-01" @default.
- W1992623361 modified "2023-10-12" @default.
- W1992623361 title "Impact of Mitral Valve Annuloplasty Combined With Revascularization in Patients With Functional Ischemic Mitral Regurgitation" @default.
- W1992623361 cites W1963998195 @default.
- W1992623361 cites W1966171934 @default.
- W1992623361 cites W1976662658 @default.
- W1992623361 cites W1978542105 @default.
- W1992623361 cites W1987905315 @default.
- W1992623361 cites W1988442237 @default.
- W1992623361 cites W1990281264 @default.
- W1992623361 cites W2001105016 @default.
- W1992623361 cites W2012279573 @default.
- W1992623361 cites W2017437692 @default.
- W1992623361 cites W2033529578 @default.
- W1992623361 cites W2039904801 @default.
- W1992623361 cites W2052351527 @default.
- W1992623361 cites W2056495130 @default.
- W1992623361 cites W2076183676 @default.
- W1992623361 cites W2094999245 @default.
- W1992623361 cites W2119298751 @default.
- W1992623361 cites W2133145982 @default.
- W1992623361 cites W2136335380 @default.
- W1992623361 cites W2140219551 @default.
- W1992623361 cites W2141769793 @default.
- W1992623361 cites W2150291618 @default.
- W1992623361 cites W2164269479 @default.
- W1992623361 cites W2169132724 @default.
- W1992623361 cites W2211479153 @default.
- W1992623361 cites W4212883601 @default.
- W1992623361 doi "https://doi.org/10.1016/j.jacc.2007.02.043" @default.
- W1992623361 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17543639" @default.
- W1992623361 hasPublicationYear "2007" @default.
- W1992623361 type Work @default.
- W1992623361 sameAs 1992623361 @default.
- W1992623361 citedByCount "416" @default.
- W1992623361 countsByYear W19926233612012 @default.
- W1992623361 countsByYear W19926233612013 @default.
- W1992623361 countsByYear W19926233612014 @default.
- W1992623361 countsByYear W19926233612015 @default.
- W1992623361 countsByYear W19926233612016 @default.
- W1992623361 countsByYear W19926233612017 @default.
- W1992623361 countsByYear W19926233612018 @default.
- W1992623361 countsByYear W19926233612019 @default.
- W1992623361 countsByYear W19926233612020 @default.
- W1992623361 countsByYear W19926233612021 @default.
- W1992623361 countsByYear W19926233612022 @default.
- W1992623361 countsByYear W19926233612023 @default.
- W1992623361 crossrefType "journal-article" @default.
- W1992623361 hasAuthorship W1992623361A5003737429 @default.
- W1992623361 hasAuthorship W1992623361A5011317354 @default.
- W1992623361 hasAuthorship W1992623361A5024406367 @default.
- W1992623361 hasAuthorship W1992623361A5034718335 @default.
- W1992623361 hasAuthorship W1992623361A5048979901 @default.
- W1992623361 hasAuthorship W1992623361A5059484584 @default.
- W1992623361 hasAuthorship W1992623361A5065932248 @default.
- W1992623361 hasAuthorship W1992623361A5073592687 @default.
- W1992623361 hasConcept C126322002 @default.
- W1992623361 hasConcept C164705383 @default.
- W1992623361 hasConcept C2775932942 @default.
- W1992623361 hasConcept C2777543888 @default.
- W1992623361 hasConcept C2778198053 @default.
- W1992623361 hasConcept C2778213512 @default.
- W1992623361 hasConcept C2779464278 @default.
- W1992623361 hasConcept C2780679668 @default.
- W1992623361 hasConcept C2780864736 @default.
- W1992623361 hasConcept C2909944400 @default.
- W1992623361 hasConcept C2993373945 @default.
- W1992623361 hasConcept C500558357 @default.
- W1992623361 hasConcept C71924100 @default.
- W1992623361 hasConcept C78085059 @default.
- W1992623361 hasConceptScore W1992623361C126322002 @default.
- W1992623361 hasConceptScore W1992623361C164705383 @default.
- W1992623361 hasConceptScore W1992623361C2775932942 @default.
- W1992623361 hasConceptScore W1992623361C2777543888 @default.
- W1992623361 hasConceptScore W1992623361C2778198053 @default.
- W1992623361 hasConceptScore W1992623361C2778213512 @default.
- W1992623361 hasConceptScore W1992623361C2779464278 @default.
- W1992623361 hasConceptScore W1992623361C2780679668 @default.
- W1992623361 hasConceptScore W1992623361C2780864736 @default.
- W1992623361 hasConceptScore W1992623361C2909944400 @default.
- W1992623361 hasConceptScore W1992623361C2993373945 @default.
- W1992623361 hasConceptScore W1992623361C500558357 @default.
- W1992623361 hasConceptScore W1992623361C71924100 @default.
- W1992623361 hasConceptScore W1992623361C78085059 @default.
- W1992623361 hasIssue "22" @default.
- W1992623361 hasLocation W19926233611 @default.
- W1992623361 hasLocation W19926233612 @default.
- W1992623361 hasOpenAccess W1992623361 @default.