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• W1992651831 abstract "The functional properties of the KOLT-2 antigen, which was placed among the CD28 group in the 3rd International Workshop on Human Leukocyte Differentiation Antigens, are described. The method of production and a detailed characterization of the monoclonal antibody KOLT-2 including stain affinities and influence of T cell activation are presented. While KOLT-2 antigen was selectively expressed on human thymocytes, adult T-cell leuke-mia-lymphoma cells and activated T cells, the antigen was also spontaneously expressed by resting T cells after 24 hrs culture. Expression was transient, since it disappeared after 96 hrs. DNA synthesis and expression of Tac antigen on activated T cells was enhanced by stimulation with the KOLT-2. These observations suggest that the KOLT-2 antigen may have an important role in the early stages of T cell activation." @default.
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• W1992651831 date "1991-01-01" @default.
• W1992651831 modified "2023-10-18" @default.
• W1992651831 title "Monoclonal Antibody KOLT-2 Enhances DNA Synthesis and Expression of IL-2 Receptors on Activated T Cells." @default.
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• W1992651831 doi "https://doi.org/10.2739/kurumemedj.38.295" @default.
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