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- W1992664308 abstract "Various derivatives of rifamycin were shown to inhibit the RNA polymerases of the yeast and mycelial phases of Histoplasma capsulatum. The relative potency of each of the derivatives against the isolated polymerases was the same as the potency of each against the viable organism. RNA polymerase PC III from the yeast phase was more susceptible to the rifamycin derivatives than yeast phase polymerases PC I and PC II and the biggest differences in susceptibility were seen with the derivative AF/ABDP (2,6-dimethyl-4-benzyl-4-demethyl-rifamycin). The susceptibility pattern of the mycelial polymerase activity was identical to the yeast polymerase PC III." @default.
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- W1992664308 date "1977-01-01" @default.
- W1992664308 modified "2023-09-25" @default.
- W1992664308 title "Inhibition of isolated yeast and mycelial phase RNA polymerases ofHistoplasma capsulatumby rifamycin derivatives" @default.
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- W1992664308 doi "https://doi.org/10.1080/00362177785380081" @default.
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