Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992672008> ?p ?o ?g. }
- W1992672008 endingPage "2964" @default.
- W1992672008 startingPage "2958" @default.
- W1992672008 abstract "In an effort to delineate the distribution of the Leu-7 antigen in small cell neoplasms, 283 paraffin-embedded examples of such tumors were studied immunohistochemically. These included 125 malignant lymphomas, 94 neuroendocrine carcinomas, 13 adenocarcinomas, 14 squamous carcinomas, four malignant melanomas, six neuroblastomas, four nephroblastomas (Wilms' tumors), six primitive neuroectodermal neoplasms, three Askin tumors, ten Ewing's sarcomas, and four embryonal rhabdomyosarcomas. Histologic diagnoses were verified by the use of electron microscopic study or independent immunostains. Overall, 44% of small cell neuroendocrine carcinomas expressed Leu-7, whereas nonendocrine carcinomas were uniformly nonreactive for this determinant. All neuroblastomas yielded immunopositivity, as did three primitive neuroectodermal tumors, three rhabdomyosarcomas, two Askin tumors, one nephroblastoma, one Ewing's sarcoma, and one malignant melanoma. None of the small cell lymphomas were Leu-7 positive. These results suggest that Leu-7 is a specific neuroendocrine marker in cases of small cell carcinoma, but its sensitivity is lower than that of other endocrine determinants. Reactivity patterns for Leu-7 in other small cell tumors demonstrate no specificity for any given line of cellular differentiation. However, the shared expression of this antigen by neuroblastomas, neuroectodermal tumors, Ewing's sarcomas, and Wilm's tumors contributes further to the hypothesis that these neoplasms may be related histogenetically." @default.
- W1992672008 created "2016-06-24" @default.
- W1992672008 creator A5007935074 @default.
- W1992672008 creator A5024634894 @default.
- W1992672008 creator A5055065582 @default.
- W1992672008 creator A5058317335 @default.
- W1992672008 date "1987-12-15" @default.
- W1992672008 modified "2023-10-16" @default.
- W1992672008 title "Leu-7 in small cell neoplasms. An immunohistochemical study with ultrastructural correlations" @default.
- W1992672008 cites W1438018833 @default.
- W1992672008 cites W1966667541 @default.
- W1992672008 cites W1972105236 @default.
- W1992672008 cites W1980927388 @default.
- W1992672008 cites W1986369391 @default.
- W1992672008 cites W1986435647 @default.
- W1992672008 cites W1987418460 @default.
- W1992672008 cites W1988804372 @default.
- W1992672008 cites W1993520706 @default.
- W1992672008 cites W1998632751 @default.
- W1992672008 cites W2005309727 @default.
- W1992672008 cites W2008709016 @default.
- W1992672008 cites W2013483011 @default.
- W1992672008 cites W2020907163 @default.
- W1992672008 cites W2027641049 @default.
- W1992672008 cites W2027874113 @default.
- W1992672008 cites W2035560879 @default.
- W1992672008 cites W2036587644 @default.
- W1992672008 cites W2049402644 @default.
- W1992672008 cites W2057091298 @default.
- W1992672008 cites W2063943183 @default.
- W1992672008 cites W2063994397 @default.
- W1992672008 cites W2067796820 @default.
- W1992672008 cites W2073006349 @default.
- W1992672008 cites W2075438418 @default.
- W1992672008 cites W2077058201 @default.
- W1992672008 cites W2080859229 @default.
- W1992672008 cites W2081512417 @default.
- W1992672008 cites W2083526422 @default.
- W1992672008 cites W2089205140 @default.
- W1992672008 cites W2096428903 @default.
- W1992672008 cites W2111865039 @default.
- W1992672008 cites W2121117520 @default.
- W1992672008 cites W2151976296 @default.
- W1992672008 cites W2162025519 @default.
- W1992672008 cites W2166617178 @default.
- W1992672008 cites W2323211500 @default.
- W1992672008 cites W2327968958 @default.
- W1992672008 cites W2885117810 @default.
- W1992672008 cites W340492828 @default.
- W1992672008 cites W4231423721 @default.
- W1992672008 cites W4297957645 @default.
- W1992672008 cites W80144156 @default.
- W1992672008 doi "https://doi.org/10.1002/1097-0142(19871215)60:12<2958::aid-cncr2820601218>3.0.co;2-j" @default.
- W1992672008 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3499971" @default.
- W1992672008 hasPublicationYear "1987" @default.
- W1992672008 type Work @default.
- W1992672008 sameAs 1992672008 @default.
- W1992672008 citedByCount "55" @default.
- W1992672008 countsByYear W19926720082013 @default.
- W1992672008 countsByYear W19926720082015 @default.
- W1992672008 countsByYear W19926720082021 @default.
- W1992672008 countsByYear W19926720082022 @default.
- W1992672008 crossrefType "journal-article" @default.
- W1992672008 hasAuthorship W1992672008A5007935074 @default.
- W1992672008 hasAuthorship W1992672008A5024634894 @default.
- W1992672008 hasAuthorship W1992672008A5055065582 @default.
- W1992672008 hasAuthorship W1992672008A5058317335 @default.
- W1992672008 hasConcept C142724271 @default.
- W1992672008 hasConcept C204232928 @default.
- W1992672008 hasConcept C2775842971 @default.
- W1992672008 hasConcept C2776715637 @default.
- W1992672008 hasConcept C2776891213 @default.
- W1992672008 hasConcept C2777546739 @default.
- W1992672008 hasConcept C2778256501 @default.
- W1992672008 hasConcept C2779292878 @default.
- W1992672008 hasConcept C2780844630 @default.
- W1992672008 hasConcept C54355233 @default.
- W1992672008 hasConcept C71924100 @default.
- W1992672008 hasConcept C81885089 @default.
- W1992672008 hasConcept C86803240 @default.
- W1992672008 hasConceptScore W1992672008C142724271 @default.
- W1992672008 hasConceptScore W1992672008C204232928 @default.
- W1992672008 hasConceptScore W1992672008C2775842971 @default.
- W1992672008 hasConceptScore W1992672008C2776715637 @default.
- W1992672008 hasConceptScore W1992672008C2776891213 @default.
- W1992672008 hasConceptScore W1992672008C2777546739 @default.
- W1992672008 hasConceptScore W1992672008C2778256501 @default.
- W1992672008 hasConceptScore W1992672008C2779292878 @default.
- W1992672008 hasConceptScore W1992672008C2780844630 @default.
- W1992672008 hasConceptScore W1992672008C54355233 @default.
- W1992672008 hasConceptScore W1992672008C71924100 @default.
- W1992672008 hasConceptScore W1992672008C81885089 @default.
- W1992672008 hasConceptScore W1992672008C86803240 @default.
- W1992672008 hasIssue "12" @default.
- W1992672008 hasLocation W19926720081 @default.
- W1992672008 hasLocation W19926720082 @default.
- W1992672008 hasOpenAccess W1992672008 @default.
- W1992672008 hasPrimaryLocation W19926720081 @default.