FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992797905> ?p ?o ?g. }

• W1992797905 endingPage "820" @default.
• W1992797905 startingPage "814" @default.
• W1992797905 abstract "Sickle cell disease is a public health problem. The WHO has recommended that global management be implemented to reduce mortality and morbidity. Since no comprehensive care programme for bone and joint complications exists, the Caribbean Sickle Cell Disease Center added orthopaedic consultation to screen for and monitor these complications in 1992.Comprehensive medical and surgical care of patients with sickle cell disease will reduce the complications and disability associated with this disease.Two populations were compared to evaluate the impact of comprehensive disease management on the occurrence of avascular necrosis (AVN) of the femoral head (femoral head AVN). The case-control series, [E-1994], included 115 patients (58 SS and 57 S) without orthopaedic monitoring and was evaluated retrospectively. The other patient series, [E-2008], included 215 patients (94 SS and 121 SC) with systematic orthopaedic care and was followed prospectively. Age, gender, duration of follow-up, haemoglobin levels, genotype, pain before treatment, associated humerus AVN and leg ulcers were analysed.Femoral head AVN occurred in young adult patients (35.3 ± 4 years for [E-1994] and 29 ± 3.4 years for [E-2008]). Only elevated haemoglobin levels were associated with the occurrence of femoral head AVN, which suggests that increased blood viscosity contributes to the condition ([E-1994], P<0.0001; [E-2008], P=0.001). Treatment in [E-2008] patients reduced the number of femoral head AVN cases from 36.5% in [E-1994] to 14.4% in [E-2008] (P<0.0001).The prevention and management of femoral head AVN must include medical treatment of the disease to reduce the occurrence of painful vaso-occlusive crises, which are known to trigger femoral head AVN. The effectiveness of this programme hinged on identifying risk factors and using simple approaches (hydration, pain medication, rest and crutches) to manage painful joint crises before femoral head AVN appeared. These approaches could be implemented in disadvantaged countries where sickle cell disease is prevalent.By knowing the risk factors, symptomatic patients who are at risk for femoral head AVN can be identified and additional evaluations can be performed early on in cases of hip pain." @default.
• W1992797905 created "2016-06-24" @default.
• W1992797905 creator A5000896186 @default.
• W1992797905 creator A5011921095 @default.
• W1992797905 creator A5014244027 @default.
• W1992797905 creator A5015781336 @default.
• W1992797905 creator A5052467612 @default.
• W1992797905 creator A5067887516 @default.
• W1992797905 date "2011-12-01" @default.
• W1992797905 modified "2023-09-29" @default.
• W1992797905 title "Risk factors and impact of orthopaedic monitoring on the outcome of avascular necrosis of the femoral head in adults with sickle cell disease: 215 patients case study with control group" @default.
• W1992797905 cites W1589883292 @default.
• W1992797905 cites W1610032264 @default.
• W1992797905 cites W1893278008 @default.
• W1992797905 cites W1947592769 @default.
• W1992797905 cites W1971591307 @default.
• W1992797905 cites W2001127294 @default.
• W1992797905 cites W2005267672 @default.
• W1992797905 cites W2015390613 @default.
• W1992797905 cites W2017248544 @default.
• W1992797905 cites W2018181483 @default.
• W1992797905 cites W2038161958 @default.
• W1992797905 cites W2058806224 @default.
• W1992797905 cites W2074399802 @default.
• W1992797905 cites W2081972626 @default.
• W1992797905 cites W2096668872 @default.
• W1992797905 cites W2103932627 @default.
• W1992797905 cites W2108294846 @default.
• W1992797905 cites W2121034648 @default.
• W1992797905 cites W2145006345 @default.
• W1992797905 cites W2150550839 @default.
• W1992797905 cites W2154186840 @default.
• W1992797905 cites W2162912931 @default.
• W1992797905 cites W2169024161 @default.
• W1992797905 cites W2209808891 @default.
• W1992797905 cites W2326691970 @default.
• W1992797905 cites W2397953172 @default.
• W1992797905 doi "https://doi.org/10.1016/j.otsr.2011.09.011" @default.
• W1992797905 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22079613" @default.
• W1992797905 hasPublicationYear "2011" @default.
• W1992797905 type Work @default.
• W1992797905 sameAs 1992797905 @default.
• W1992797905 citedByCount "25" @default.
• W1992797905 countsByYear W19927979052013 @default.
• W1992797905 countsByYear W19927979052014 @default.
• W1992797905 countsByYear W19927979052015 @default.
• W1992797905 countsByYear W19927979052016 @default.
• W1992797905 countsByYear W19927979052017 @default.
• W1992797905 countsByYear W19927979052018 @default.
• W1992797905 countsByYear W19927979052019 @default.
• W1992797905 countsByYear W19927979052020 @default.
• W1992797905 countsByYear W19927979052021 @default.
• W1992797905 countsByYear W19927979052022 @default.
• W1992797905 countsByYear W19927979052023 @default.
• W1992797905 crossrefType "journal-article" @default.
• W1992797905 hasAuthorship W1992797905A5000896186 @default.
• W1992797905 hasAuthorship W1992797905A5011921095 @default.
• W1992797905 hasAuthorship W1992797905A5014244027 @default.
• W1992797905 hasAuthorship W1992797905A5015781336 @default.
• W1992797905 hasAuthorship W1992797905A5052467612 @default.
• W1992797905 hasAuthorship W1992797905A5067887516 @default.
• W1992797905 hasBestOaLocation W19927979051 @default.
• W1992797905 hasConcept C126322002 @default.
• W1992797905 hasConcept C141071460 @default.
• W1992797905 hasConcept C2777560053 @default.
• W1992797905 hasConcept C2779100257 @default.
• W1992797905 hasConcept C2779134260 @default.
• W1992797905 hasConcept C68312169 @default.
• W1992797905 hasConcept C71924100 @default.
• W1992797905 hasConceptScore W1992797905C126322002 @default.
• W1992797905 hasConceptScore W1992797905C141071460 @default.
• W1992797905 hasConceptScore W1992797905C2777560053 @default.
• W1992797905 hasConceptScore W1992797905C2779100257 @default.
• W1992797905 hasConceptScore W1992797905C2779134260 @default.
• W1992797905 hasConceptScore W1992797905C68312169 @default.
• W1992797905 hasConceptScore W1992797905C71924100 @default.
• W1992797905 hasIssue "8" @default.
• W1992797905 hasLocation W19927979051 @default.
• W1992797905 hasLocation W19927979052 @default.
• W1992797905 hasOpenAccess W1992797905 @default.
• W1992797905 hasPrimaryLocation W19927979051 @default.
• W1992797905 hasRelatedWork W1602674271 @default.
• W1992797905 hasRelatedWork W2050511753 @default.
• W1992797905 hasRelatedWork W2072268594 @default.
• W1992797905 hasRelatedWork W2086906513 @default.
• W1992797905 hasRelatedWork W2134991248 @default.
• W1992797905 hasRelatedWork W2356796574 @default.
• W1992797905 hasRelatedWork W2412654462 @default.
• W1992797905 hasRelatedWork W2431044021 @default.
• W1992797905 hasRelatedWork W2906552209 @default.
• W1992797905 hasRelatedWork W4236048475 @default.
• W1992797905 hasVolume "97" @default.
• W1992797905 isParatext "false" @default.
• W1992797905 isRetracted "false" @default.
• W1992797905 magId "1992797905" @default.
• W1992797905 workType "article" @default.