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- W1992862012 abstract "The aim of this tutorial review is to introduce the reader to the concept, synthesis and application of natural product-inspired compound collections as an important field in chemical biology. This review will discuss how potentially interesting scaffolds can be identified (structural classification of natural products), synthesized in an appropriate manner (including stereoselective transformations for solid phase-bound compounds) and tested in biological assays (cell-based screening as well as biochemical in vitro assays). These approaches will provide the opportunity to identify new and interesting compounds as well as new targets for chemical biology and medicinal chemistry research." @default.
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- W1992862012 date "2008-01-01" @default.
- W1992862012 modified "2023-10-15" @default.
- W1992862012 title "Chemical biology—identification of small molecule modulators of cellular activity by natural product inspired synthesis" @default.
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- W1992862012 doi "https://doi.org/10.1039/b704729k" @default.
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