Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992893207> ?p ?o ?g. }
- W1992893207 endingPage "72" @default.
- W1992893207 startingPage "65" @default.
- W1992893207 abstract "Viruses have been invaluable tools for discovering key pathways of nucleocytoplasmic transport. Conversely, disruption of specific nuclear transport pathways, are crucial for the productive life cycle of some viruses. The major cellular mRNA export pathway, which uses TAP (NXF1)/p15(NXT) as receptor, was discovered as a result of TAP interaction with CTE-containing RNAs from Mason-Pfizer Monkey Virus. In addition, CRM1 or exportin 1, which is a transport receptor that mediates nuclear export of proteins, snRNAs, rRNAs and a small subset of mRNAs, was discovered as an interacting partner of the Rev protein of HIV1. Viruses may disrupt the nuclear transport machinery to prevent host antiviral response. VSV Matrix (M) protein inhibits mRNA export by forming a complex with the mRNA export factor Rae1 whereas poliovirus inhibits nuclear import of proteins by probably degrading Nup62 and Nup153. Hence, this review focuses on viruses as tools and as disruptors of nucleocytoplasmic trafficking. IUBMB Life, 57: 65-72, 2005" @default.
- W1992893207 created "2016-06-24" @default.
- W1992893207 creator A5014882971 @default.
- W1992893207 creator A5023349492 @default.
- W1992893207 creator A5053929653 @default.
- W1992893207 date "2005-02-01" @default.
- W1992893207 modified "2023-09-27" @default.
- W1992893207 title "Viral Interactions with the Nuclear Transport Machinery: Discovering and Disrupting Pathways" @default.
- W1992893207 cites W1542691850 @default.
- W1992893207 cites W1964916693 @default.
- W1992893207 cites W1967225591 @default.
- W1992893207 cites W1977820220 @default.
- W1992893207 cites W1981457569 @default.
- W1992893207 cites W1984013070 @default.
- W1992893207 cites W1997250436 @default.
- W1992893207 cites W2000570159 @default.
- W1992893207 cites W2000859947 @default.
- W1992893207 cites W2004849389 @default.
- W1992893207 cites W2005228651 @default.
- W1992893207 cites W2005855998 @default.
- W1992893207 cites W2011052397 @default.
- W1992893207 cites W2014001404 @default.
- W1992893207 cites W2014730746 @default.
- W1992893207 cites W2015625581 @default.
- W1992893207 cites W2017284082 @default.
- W1992893207 cites W2017354051 @default.
- W1992893207 cites W2019944861 @default.
- W1992893207 cites W2020167518 @default.
- W1992893207 cites W2021026930 @default.
- W1992893207 cites W2022546135 @default.
- W1992893207 cites W2026512609 @default.
- W1992893207 cites W2028885314 @default.
- W1992893207 cites W2032014779 @default.
- W1992893207 cites W2033739453 @default.
- W1992893207 cites W2037534409 @default.
- W1992893207 cites W2040516035 @default.
- W1992893207 cites W2040705986 @default.
- W1992893207 cites W2049369269 @default.
- W1992893207 cites W2050908337 @default.
- W1992893207 cites W2058016035 @default.
- W1992893207 cites W2061637725 @default.
- W1992893207 cites W2069490539 @default.
- W1992893207 cites W2075488235 @default.
- W1992893207 cites W2079357798 @default.
- W1992893207 cites W2084711835 @default.
- W1992893207 cites W2092499288 @default.
- W1992893207 cites W2098238189 @default.
- W1992893207 cites W2113927132 @default.
- W1992893207 cites W2124160523 @default.
- W1992893207 cites W2127901995 @default.
- W1992893207 cites W2127954678 @default.
- W1992893207 cites W2129446623 @default.
- W1992893207 cites W2140788063 @default.
- W1992893207 cites W2144564747 @default.
- W1992893207 cites W2150701651 @default.
- W1992893207 cites W2153504753 @default.
- W1992893207 cites W2155085170 @default.
- W1992893207 cites W2171167766 @default.
- W1992893207 cites W2171258458 @default.
- W1992893207 cites W74897047 @default.
- W1992893207 doi "https://doi.org/10.1080/15216540500078608" @default.
- W1992893207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16036565" @default.
- W1992893207 hasPublicationYear "2005" @default.
- W1992893207 type Work @default.
- W1992893207 sameAs 1992893207 @default.
- W1992893207 citedByCount "52" @default.
- W1992893207 countsByYear W19928932072012 @default.
- W1992893207 countsByYear W19928932072013 @default.
- W1992893207 countsByYear W19928932072014 @default.
- W1992893207 countsByYear W19928932072015 @default.
- W1992893207 countsByYear W19928932072016 @default.
- W1992893207 countsByYear W19928932072017 @default.
- W1992893207 countsByYear W19928932072018 @default.
- W1992893207 countsByYear W19928932072019 @default.
- W1992893207 countsByYear W19928932072020 @default.
- W1992893207 countsByYear W19928932072021 @default.
- W1992893207 countsByYear W19928932072022 @default.
- W1992893207 countsByYear W19928932072023 @default.
- W1992893207 crossrefType "journal-article" @default.
- W1992893207 hasAuthorship W1992893207A5014882971 @default.
- W1992893207 hasAuthorship W1992893207A5023349492 @default.
- W1992893207 hasAuthorship W1992893207A5053929653 @default.
- W1992893207 hasBestOaLocation W19928932071 @default.
- W1992893207 hasConcept C104317684 @default.
- W1992893207 hasConcept C105580179 @default.
- W1992893207 hasConcept C126725582 @default.
- W1992893207 hasConcept C160704184 @default.
- W1992893207 hasConcept C2780114586 @default.
- W1992893207 hasConcept C2780723820 @default.
- W1992893207 hasConcept C54355233 @default.
- W1992893207 hasConcept C54757728 @default.
- W1992893207 hasConcept C59157529 @default.
- W1992893207 hasConcept C68556195 @default.
- W1992893207 hasConcept C86803240 @default.
- W1992893207 hasConcept C95444343 @default.
- W1992893207 hasConceptScore W1992893207C104317684 @default.
- W1992893207 hasConceptScore W1992893207C105580179 @default.
- W1992893207 hasConceptScore W1992893207C126725582 @default.