FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992905836> ?p ?o ?g. }

• W1992905836 endingPage "479" @default.
• W1992905836 startingPage "469" @default.
• W1992905836 abstract "In the field of cell and tissue engineering, culture expansion of human cells in monolayer plays an important part. Traditionally, cell cultures have been supplemented with serum to support attachment and proliferation, but serum is a potential source of foreign protein contamination and viral protein transmission. In this study, we evaluated the use of human serum for experimental human articular chondrocyte expansion and to develop a method for preparation of large volumes of high-quality human serum from healthy blood donors. Human autologous serum contained high levels of epidermal-derived growth factor and platelet-derived growth factor-AB and supported proliferation up to 7 times higher than FCS in primary chondrocyte cultures. By letting the coagulation take place in a commercially available transfusion bag overnight, up to 250 ml of growth factor-rich human serum could be obtained from one donor. The allogenic human serum supported high proliferation rate without loosing expression of cartilage-specific genes. The expanded chondrocytes were able to redifferentiate and form cartilage matrix in comparable amounts to autologous serums. In conclusion, the transfusion bags allow preparation of large volumes of growth factor-rich human serum with the capacity to support in vitro cell expansion. The data further indicate that by controlling the coagulation process there are possibilities of optimizing the release of growth factors for other emerging cell therapies." @default.
• W1992905836 created "2016-06-24" @default.
• W1992905836 creator A5011583053 @default.
• W1992905836 creator A5020471341 @default.
• W1992905836 creator A5022018993 @default.
• W1992905836 creator A5038842105 @default.
• W1992905836 creator A5062854327 @default.
• W1992905836 creator A5079499378 @default.
• W1992905836 date "2005-08-01" @default.
• W1992905836 modified "2023-09-25" @default.
• W1992905836 title "Human Serum for Culture of Articular Chondrocytes" @default.
• W1992905836 cites W11305555 @default.
• W1992905836 cites W1544751778 @default.
• W1992905836 cites W1805858026 @default.
• W1992905836 cites W192836234 @default.
• W1992905836 cites W1965823380 @default.
• W1992905836 cites W1978716021 @default.
• W1992905836 cites W1978963263 @default.
• W1992905836 cites W1979684462 @default.
• W1992905836 cites W1983167228 @default.
• W1992905836 cites W1986520410 @default.
• W1992905836 cites W1988592246 @default.
• W1992905836 cites W1992075337 @default.
• W1992905836 cites W1996247217 @default.
• W1992905836 cites W2008434750 @default.
• W1992905836 cites W2009988928 @default.
• W1992905836 cites W2012738478 @default.
• W1992905836 cites W2018362210 @default.
• W1992905836 cites W2028391361 @default.
• W1992905836 cites W2032255522 @default.
• W1992905836 cites W2032372303 @default.
• W1992905836 cites W2034250100 @default.
• W1992905836 cites W2036553623 @default.
• W1992905836 cites W2036647569 @default.
• W1992905836 cites W2050273631 @default.
• W1992905836 cites W2066581346 @default.
• W1992905836 cites W2079801691 @default.
• W1992905836 cites W2099543104 @default.
• W1992905836 cites W2124052926 @default.
• W1992905836 cites W2153828239 @default.
• W1992905836 cites W2161887455 @default.
• W1992905836 cites W2419391895 @default.
• W1992905836 doi "https://doi.org/10.3727/000000005783982909" @default.
• W1992905836 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16285255" @default.
• W1992905836 hasPublicationYear "2005" @default.
• W1992905836 type Work @default.
• W1992905836 sameAs 1992905836 @default.
• W1992905836 citedByCount "53" @default.
• W1992905836 countsByYear W19929058362012 @default.
• W1992905836 countsByYear W19929058362013 @default.
• W1992905836 countsByYear W19929058362014 @default.
• W1992905836 countsByYear W19929058362015 @default.
• W1992905836 countsByYear W19929058362017 @default.
• W1992905836 countsByYear W19929058362018 @default.
• W1992905836 countsByYear W19929058362019 @default.
• W1992905836 countsByYear W19929058362020 @default.
• W1992905836 countsByYear W19929058362021 @default.
• W1992905836 countsByYear W19929058362022 @default.
• W1992905836 crossrefType "journal-article" @default.
• W1992905836 hasAuthorship W1992905836A5011583053 @default.
• W1992905836 hasAuthorship W1992905836A5020471341 @default.
• W1992905836 hasAuthorship W1992905836A5022018993 @default.
• W1992905836 hasAuthorship W1992905836A5038842105 @default.
• W1992905836 hasAuthorship W1992905836A5062854327 @default.
• W1992905836 hasAuthorship W1992905836A5079499378 @default.
• W1992905836 hasConcept C105702510 @default.
• W1992905836 hasConcept C126322002 @default.
• W1992905836 hasConcept C136229726 @default.
• W1992905836 hasConcept C16685009 @default.
• W1992905836 hasConcept C170493617 @default.
• W1992905836 hasConcept C185592680 @default.
• W1992905836 hasConcept C202751555 @default.
• W1992905836 hasConcept C203014093 @default.
• W1992905836 hasConcept C2775960820 @default.
• W1992905836 hasConcept C2776362946 @default.
• W1992905836 hasConcept C2776662772 @default.
• W1992905836 hasConcept C2778382381 @default.
• W1992905836 hasConcept C2780550940 @default.
• W1992905836 hasConcept C2781403057 @default.
• W1992905836 hasConcept C49892992 @default.
• W1992905836 hasConcept C54355233 @default.
• W1992905836 hasConcept C55493867 @default.
• W1992905836 hasConcept C62112901 @default.
• W1992905836 hasConcept C71924100 @default.
• W1992905836 hasConcept C81885089 @default.
• W1992905836 hasConcept C86803240 @default.
• W1992905836 hasConcept C89560881 @default.
• W1992905836 hasConcept C95444343 @default.
• W1992905836 hasConceptScore W1992905836C105702510 @default.
• W1992905836 hasConceptScore W1992905836C126322002 @default.
• W1992905836 hasConceptScore W1992905836C136229726 @default.
• W1992905836 hasConceptScore W1992905836C16685009 @default.
• W1992905836 hasConceptScore W1992905836C170493617 @default.
• W1992905836 hasConceptScore W1992905836C185592680 @default.
• W1992905836 hasConceptScore W1992905836C202751555 @default.
• W1992905836 hasConceptScore W1992905836C203014093 @default.
• W1992905836 hasConceptScore W1992905836C2775960820 @default.
• W1992905836 hasConceptScore W1992905836C2776362946 @default.

• next