Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992912287> ?p ?o ?g. }
- W1992912287 endingPage "e73871" @default.
- W1992912287 startingPage "e73871" @default.
- W1992912287 abstract "Background A candidate vaccine, live attenuated Vibrio anguillarum developed in our laboratory could prevent vibriosis of fish resulted from V. anguillarum and V. alginolyticus. To elucidate the molecular mechanisms underlying the vaccine protection, we used microarray technology to compare the spleen transcriptomes of bath-vaccinated and unvaccinated zebrafish at 28 days post vaccination. Principal Findings A total of 2164 genes and transcripts were differentially expressed, accounting for 4.9% of all genes represented on the chip. In addition to iron metabolism related to the innate immunity and the signaling pathways, these differentially expressed genes also involved in the adaptive immunity, mainly including the genes associated with B and T cells activation, proliferation and expansion. Transcription profiles of Th17-related transcription factors, cytokines and cytokine receptors during 35 days post-vaccination implied that Th17 cells be activated in bath-vaccinated zebrafish. Conclusion/Significance The transcriptome profiling with microarray revealed the Th17-like immune response to bath-vaccination with the live attenuated V. anguillarum in zebrafish." @default.
- W1992912287 created "2016-06-24" @default.
- W1992912287 creator A5000389309 @default.
- W1992912287 creator A5020022791 @default.
- W1992912287 creator A5031283520 @default.
- W1992912287 creator A5050517861 @default.
- W1992912287 creator A5056450584 @default.
- W1992912287 creator A5084732119 @default.
- W1992912287 creator A5088303206 @default.
- W1992912287 date "2013-09-04" @default.
- W1992912287 modified "2023-09-27" @default.
- W1992912287 title "Transcriptome Profiling Reveals Th17-Like Immune Responses Induced in Zebrafish Bath-Vaccinated with a Live Attenuated Vibrio anguillarum" @default.
- W1992912287 cites W1560571961 @default.
- W1992912287 cites W1590885644 @default.
- W1992912287 cites W1603855018 @default.
- W1992912287 cites W1625264278 @default.
- W1992912287 cites W1964052073 @default.
- W1992912287 cites W1972073034 @default.
- W1992912287 cites W1974595623 @default.
- W1992912287 cites W1977812814 @default.
- W1992912287 cites W1984420944 @default.
- W1992912287 cites W1988479633 @default.
- W1992912287 cites W1998895238 @default.
- W1992912287 cites W2002148098 @default.
- W1992912287 cites W2004607223 @default.
- W1992912287 cites W2005993855 @default.
- W1992912287 cites W2007359758 @default.
- W1992912287 cites W2009382868 @default.
- W1992912287 cites W2012680181 @default.
- W1992912287 cites W2015006881 @default.
- W1992912287 cites W2020705936 @default.
- W1992912287 cites W2027772747 @default.
- W1992912287 cites W2033100064 @default.
- W1992912287 cites W2034778776 @default.
- W1992912287 cites W2035610480 @default.
- W1992912287 cites W2041572974 @default.
- W1992912287 cites W2049372707 @default.
- W1992912287 cites W2055136186 @default.
- W1992912287 cites W2096682152 @default.
- W1992912287 cites W2105668129 @default.
- W1992912287 cites W2107066107 @default.
- W1992912287 cites W2111888415 @default.
- W1992912287 cites W2114963537 @default.
- W1992912287 cites W2121682731 @default.
- W1992912287 cites W2125355878 @default.
- W1992912287 cites W2131742076 @default.
- W1992912287 cites W2137341140 @default.
- W1992912287 cites W2139008734 @default.
- W1992912287 cites W2145319582 @default.
- W1992912287 cites W2149926345 @default.
- W1992912287 cites W2150740381 @default.
- W1992912287 cites W2155779547 @default.
- W1992912287 cites W2160258620 @default.
- W1992912287 cites W2160883911 @default.
- W1992912287 cites W2163115732 @default.
- W1992912287 cites W2165350202 @default.
- W1992912287 cites W2169450299 @default.
- W1992912287 cites W2170904230 @default.
- W1992912287 cites W2172094131 @default.
- W1992912287 cites W2776663677 @default.
- W1992912287 cites W4235022528 @default.
- W1992912287 cites W4235338639 @default.
- W1992912287 doi "https://doi.org/10.1371/journal.pone.0073871" @default.
- W1992912287 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3762715" @default.
- W1992912287 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24023910" @default.
- W1992912287 hasPublicationYear "2013" @default.
- W1992912287 type Work @default.
- W1992912287 sameAs 1992912287 @default.
- W1992912287 citedByCount "33" @default.
- W1992912287 countsByYear W19929122872014 @default.
- W1992912287 countsByYear W19929122872015 @default.
- W1992912287 countsByYear W19929122872016 @default.
- W1992912287 countsByYear W19929122872017 @default.
- W1992912287 countsByYear W19929122872018 @default.
- W1992912287 countsByYear W19929122872019 @default.
- W1992912287 countsByYear W19929122872020 @default.
- W1992912287 countsByYear W19929122872021 @default.
- W1992912287 countsByYear W19929122872022 @default.
- W1992912287 countsByYear W19929122872023 @default.
- W1992912287 crossrefType "journal-article" @default.
- W1992912287 hasAuthorship W1992912287A5000389309 @default.
- W1992912287 hasAuthorship W1992912287A5020022791 @default.
- W1992912287 hasAuthorship W1992912287A5031283520 @default.
- W1992912287 hasAuthorship W1992912287A5050517861 @default.
- W1992912287 hasAuthorship W1992912287A5056450584 @default.
- W1992912287 hasAuthorship W1992912287A5084732119 @default.
- W1992912287 hasAuthorship W1992912287A5088303206 @default.
- W1992912287 hasBestOaLocation W19929122871 @default.
- W1992912287 hasConcept C104317684 @default.
- W1992912287 hasConcept C136449434 @default.
- W1992912287 hasConcept C150194340 @default.
- W1992912287 hasConcept C162317418 @default.
- W1992912287 hasConcept C18431079 @default.
- W1992912287 hasConcept C186836561 @default.
- W1992912287 hasConcept C193419808 @default.
- W1992912287 hasConcept C203014093 @default.
- W1992912287 hasConcept C22070199 @default.
- W1992912287 hasConcept C2776154503 @default.