FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992924105> ?p ?o ?g. }

• W1992924105 endingPage "213" @default.
• W1992924105 startingPage "209" @default.
• W1992924105 abstract "A member of the second-generation sulfonylureas, glyburide (GLY; glibenclamide) provides an effective therapy for patients with type 2 diabetes. It stimulates pancreatic insulin secretion, suggesting that it is effective in the treatment of type 2 diabetes primarily by elevating the circulating insulin levels. However, experimental evidences have indicated that sulfonylureas have also had an extrapancreatic effect, which may directly contribute toward maintaining blood glucose homeostasis during diabetes.In this study, we administrated GLY to streptozotocin-induced diabetic rats and determined the effects of such treatment on activities of superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GPx) from brain tissue.Brain CAT and GPx activities were not significantly different in the diabetic group compared to controls (P>.05), but the SOD activity was significantly reduced in the diabetic group compared to controls (P<.001). GLY treatment of 4 weeks had restored the SOD and CAT enzyme activities in diabetic rat brain (P<.05). In addition, high blood glucose levels of untreated diabetic rats were decreased following the GLY treatment (P<.01). Administration of GLY to diabetic rats restored the diabetes-induced changes, suggesting that GLY could restore the brain SOD and CAT activities." @default.
• W1992924105 created "2016-06-24" @default.
• W1992924105 creator A5002064195 @default.
• W1992924105 creator A5079516972 @default.
• W1992924105 creator A5089482978 @default.
• W1992924105 date "2009-05-01" @default.
• W1992924105 modified "2023-09-30" @default.
• W1992924105 title "The effects of sulfonylurea glyburide on superoxide dismutase, catalase, and glutathione peroxidase activities in the brain tissue of streptozotocin-induced diabetic rat" @default.
• W1992924105 cites W1775749144 @default.
• W1992924105 cites W191793640 @default.
• W1992924105 cites W1953115230 @default.
• W1992924105 cites W1963799565 @default.
• W1992924105 cites W1976380907 @default.
• W1992924105 cites W1986157636 @default.
• W1992924105 cites W1994327771 @default.
• W1992924105 cites W2005502331 @default.
• W1992924105 cites W2019708114 @default.
• W1992924105 cites W2032953905 @default.
• W1992924105 cites W2048243713 @default.
• W1992924105 cites W2049465069 @default.
• W1992924105 cites W2053746465 @default.
• W1992924105 cites W2054360287 @default.
• W1992924105 cites W2055514808 @default.
• W1992924105 cites W2060049759 @default.
• W1992924105 cites W2060847598 @default.
• W1992924105 cites W2060863460 @default.
• W1992924105 cites W2061441650 @default.
• W1992924105 cites W2071338573 @default.
• W1992924105 cites W2074687883 @default.
• W1992924105 cites W2076847336 @default.
• W1992924105 cites W2079822311 @default.
• W1992924105 cites W2083622913 @default.
• W1992924105 cites W2094943143 @default.
• W1992924105 cites W2104622496 @default.
• W1992924105 cites W2108477256 @default.
• W1992924105 cites W2119454481 @default.
• W1992924105 cites W2120212319 @default.
• W1992924105 cites W2123279010 @default.
• W1992924105 cites W2124098523 @default.
• W1992924105 cites W2132335976 @default.
• W1992924105 cites W2142047675 @default.
• W1992924105 cites W2157346067 @default.
• W1992924105 cites W4247735996 @default.
• W1992924105 cites W4362209258 @default.
• W1992924105 doi "https://doi.org/10.1016/j.jdiacomp.2007.09.001" @default.
• W1992924105 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18413155" @default.
• W1992924105 hasPublicationYear "2009" @default.
• W1992924105 type Work @default.
• W1992924105 sameAs 1992924105 @default.
• W1992924105 citedByCount "28" @default.
• W1992924105 countsByYear W19929241052012 @default.
• W1992924105 countsByYear W19929241052013 @default.
• W1992924105 countsByYear W19929241052015 @default.
• W1992924105 countsByYear W19929241052016 @default.
• W1992924105 countsByYear W19929241052017 @default.
• W1992924105 countsByYear W19929241052018 @default.
• W1992924105 countsByYear W19929241052019 @default.
• W1992924105 countsByYear W19929241052020 @default.
• W1992924105 countsByYear W19929241052022 @default.
• W1992924105 countsByYear W19929241052023 @default.
• W1992924105 crossrefType "journal-article" @default.
• W1992924105 hasAuthorship W1992924105A5002064195 @default.
• W1992924105 hasAuthorship W1992924105A5079516972 @default.
• W1992924105 hasAuthorship W1992924105A5089482978 @default.
• W1992924105 hasConcept C126322002 @default.
• W1992924105 hasConcept C134018914 @default.
• W1992924105 hasConcept C2775838275 @default.
• W1992924105 hasConcept C2776151105 @default.
• W1992924105 hasConcept C2778760513 @default.
• W1992924105 hasConcept C2778979269 @default.
• W1992924105 hasConcept C2779280383 @default.
• W1992924105 hasConcept C2779306644 @default.
• W1992924105 hasConcept C2779768347 @default.
• W1992924105 hasConcept C555293320 @default.
• W1992924105 hasConcept C71924100 @default.
• W1992924105 hasConceptScore W1992924105C126322002 @default.
• W1992924105 hasConceptScore W1992924105C134018914 @default.
• W1992924105 hasConceptScore W1992924105C2775838275 @default.
• W1992924105 hasConceptScore W1992924105C2776151105 @default.
• W1992924105 hasConceptScore W1992924105C2778760513 @default.
• W1992924105 hasConceptScore W1992924105C2778979269 @default.
• W1992924105 hasConceptScore W1992924105C2779280383 @default.
• W1992924105 hasConceptScore W1992924105C2779306644 @default.
• W1992924105 hasConceptScore W1992924105C2779768347 @default.
• W1992924105 hasConceptScore W1992924105C555293320 @default.
• W1992924105 hasConceptScore W1992924105C71924100 @default.
• W1992924105 hasIssue "3" @default.
• W1992924105 hasLocation W19929241051 @default.
• W1992924105 hasLocation W19929241052 @default.
• W1992924105 hasOpenAccess W1992924105 @default.
• W1992924105 hasPrimaryLocation W19929241051 @default.
• W1992924105 hasRelatedWork W1993316077 @default.
• W1992924105 hasRelatedWork W2003485540 @default.
• W1992924105 hasRelatedWork W2019604928 @default.
• W1992924105 hasRelatedWork W2058117454 @default.
• W1992924105 hasRelatedWork W2068108356 @default.
• W1992924105 hasRelatedWork W2095174320 @default.
• W1992924105 hasRelatedWork W2185010794 @default.

• next