Matches in SemOpenAlex for { <https://semopenalex.org/work/W1992971392> ?p ?o ?g. }
- W1992971392 endingPage "1374" @default.
- W1992971392 startingPage "1360" @default.
- W1992971392 abstract "The objective of this study was to evaluate the osteoinductivity of composite chitosan-nano-hydroxyapatite scaffolds in a rat muscle pouch model. Previous in vitro characterization demonstrated the ability of the scaffolds to promote bone regeneration and as a carrier for local delivery of BMP-2. Composite microspheres were prepared using a co-precipitation method, and scaffolds were fabricated using an acid wash to adhere beads together. To determine the in vivo osteoinductivity of the scaffolds, the following groups (n = 6) were implanted into muscle pouches created in the latissimus dorsi of Sprague Dawley rats: (A) lyophilized scaffolds without rhBMP-2, (B) lyophilized scaffolds with rhBMP-2, (C) non-lyophilized scaffolds with rhBMP-2, and (D) absorbable collagen sponge with rhBMP-2 (control). Groups B, C, and D were loaded with 4 mL of a 9.0 μg/mL solution of rhBMP-2 for 48 h. The rats were sacrificed after one month and samples were analyzed for amount of residual implant material, new bone, and osteoid. Although the experimental groups displayed minimal degradation after one month, all of the scaffolds contained small amounts of woven bone and considerable amounts of osteoid. Approximately thirty percent of the open space available for tissue ingrowth in the scaffolds contained new bone or osteoid in the process of mineralization. The ability of the composite scaffolds (with and without BMP-2) to promote ectopic bone growth in vivo was demonstrated." @default.
- W1992971392 created "2016-06-24" @default.
- W1992971392 creator A5003385153 @default.
- W1992971392 creator A5015650680 @default.
- W1992971392 creator A5072505598 @default.
- W1992971392 creator A5075735566 @default.
- W1992971392 date "2011-08-02" @default.
- W1992971392 modified "2023-09-27" @default.
- W1992971392 title "Osteoinductivity Assessment of BMP-2 Loaded Composite Chitosan-Nano-Hydroxyapatite Scaffolds in a Rat Muscle Pouch" @default.
- W1992971392 cites W1624686879 @default.
- W1992971392 cites W1969143454 @default.
- W1992971392 cites W1978351659 @default.
- W1992971392 cites W1984734563 @default.
- W1992971392 cites W1985862595 @default.
- W1992971392 cites W1991562420 @default.
- W1992971392 cites W1993381756 @default.
- W1992971392 cites W1994568438 @default.
- W1992971392 cites W2001902689 @default.
- W1992971392 cites W2013647096 @default.
- W1992971392 cites W2015098109 @default.
- W1992971392 cites W2016346790 @default.
- W1992971392 cites W2023063762 @default.
- W1992971392 cites W2028305494 @default.
- W1992971392 cites W2030409569 @default.
- W1992971392 cites W2034805293 @default.
- W1992971392 cites W2036495078 @default.
- W1992971392 cites W2037288613 @default.
- W1992971392 cites W2037349387 @default.
- W1992971392 cites W2039600788 @default.
- W1992971392 cites W2040272006 @default.
- W1992971392 cites W2041452182 @default.
- W1992971392 cites W2042869666 @default.
- W1992971392 cites W2044220763 @default.
- W1992971392 cites W2045095867 @default.
- W1992971392 cites W2049646476 @default.
- W1992971392 cites W2053307155 @default.
- W1992971392 cites W2054250293 @default.
- W1992971392 cites W2055476008 @default.
- W1992971392 cites W2058143379 @default.
- W1992971392 cites W2059526123 @default.
- W1992971392 cites W2061024977 @default.
- W1992971392 cites W2062762626 @default.
- W1992971392 cites W2063142742 @default.
- W1992971392 cites W2065386894 @default.
- W1992971392 cites W2066518402 @default.
- W1992971392 cites W2068532127 @default.
- W1992971392 cites W2071570004 @default.
- W1992971392 cites W2072243231 @default.
- W1992971392 cites W2074378126 @default.
- W1992971392 cites W2077994745 @default.
- W1992971392 cites W2084156852 @default.
- W1992971392 cites W2087252391 @default.
- W1992971392 cites W2093323849 @default.
- W1992971392 cites W2093837952 @default.
- W1992971392 cites W2095252431 @default.
- W1992971392 cites W2095880169 @default.
- W1992971392 cites W2097474178 @default.
- W1992971392 cites W2109189041 @default.
- W1992971392 cites W2115746002 @default.
- W1992971392 cites W2119262781 @default.
- W1992971392 cites W2121331825 @default.
- W1992971392 cites W2121661142 @default.
- W1992971392 cites W2122580836 @default.
- W1992971392 cites W2123614907 @default.
- W1992971392 cites W2133819222 @default.
- W1992971392 cites W2143228190 @default.
- W1992971392 cites W2144255775 @default.
- W1992971392 cites W2146198052 @default.
- W1992971392 cites W2152878933 @default.
- W1992971392 cites W2156611734 @default.
- W1992971392 cites W2156960174 @default.
- W1992971392 cites W2159210886 @default.
- W1992971392 cites W2161515689 @default.
- W1992971392 cites W2162988326 @default.
- W1992971392 cites W2168902269 @default.
- W1992971392 cites W2293758038 @default.
- W1992971392 cites W33772885 @default.
- W1992971392 cites W7442885 @default.
- W1992971392 doi "https://doi.org/10.3390/ma4081360" @default.
- W1992971392 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5448678" @default.
- W1992971392 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/28824147" @default.
- W1992971392 hasPublicationYear "2011" @default.
- W1992971392 type Work @default.
- W1992971392 sameAs 1992971392 @default.
- W1992971392 citedByCount "17" @default.
- W1992971392 countsByYear W19929713922013 @default.
- W1992971392 countsByYear W19929713922014 @default.
- W1992971392 countsByYear W19929713922015 @default.
- W1992971392 countsByYear W19929713922017 @default.
- W1992971392 countsByYear W19929713922019 @default.
- W1992971392 countsByYear W19929713922020 @default.
- W1992971392 countsByYear W19929713922021 @default.
- W1992971392 countsByYear W19929713922022 @default.
- W1992971392 countsByYear W19929713922023 @default.
- W1992971392 crossrefType "journal-article" @default.
- W1992971392 hasAuthorship W1992971392A5003385153 @default.
- W1992971392 hasAuthorship W1992971392A5015650680 @default.
- W1992971392 hasAuthorship W1992971392A5072505598 @default.