Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993051142> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W1993051142 endingPage "356" @default.
- W1993051142 startingPage "351" @default.
- W1993051142 abstract "The widespread use of intraarterial thrombolytic therapy has been based on perceived benefits over operative treatment and the downgrading of the magnitude of subsequent surgery. Thirty-three patients who had thrombolysis for peripheral artery occlusion were retrospectively analyzed at St. James's Hospital from 1991 to 1997. One patient received streptokinase unsuccessfully. Five other patient's records were inadequate for analysis. Twenty-seven patient's notes were analyzed for risk, duration of occlusion, duration of treatment, dosage of tissue plasminogen activator (tPA) and conduits thrombolysed. There were 15 males and 12 females. The mean age was 62 years (range, 20-87). Fourteen were current or reformed smokers. Five were diabetic. Indications for treatment included acute graft occlusion (n=13), embolus (n=6), and primary and secondary arterial thrombosis (n=8). Duration of occlusion was less than 24 hours in seven, 1 to 7 days in ten, and more than 7 days in ten patients. Twelve (44.44%) patients had complete clot lysis, four (14.81%) had partial clearance, and 11 (40.74%) remained occluded. Eight (29.63%) had serious complications including one death. Eighteen (66.66%) patients needed further surgical intervention to maintain graft patency. Data were analyzed using the chi-square and pooled t test. No significant difference was observed in results from thrombolysis from different conduits, gender, etiology, or smoking history. Increased duration of tPA administration was associated with an increased risk of failure. Administration of total dosages greater than 60 mg was associated with a higher risk of failure. Diabetics had a poor outcome (p=0.0520). Only 44 % of patients successfully underwent lysis. A primary surgical option may be a more sensible course than lysis, given that the vast majority of patients ended up having surgery anyway." @default.
- W1993051142 created "2016-06-24" @default.
- W1993051142 creator A5003141413 @default.
- W1993051142 creator A5013092596 @default.
- W1993051142 creator A5018276827 @default.
- W1993051142 creator A5024320307 @default.
- W1993051142 creator A5029276776 @default.
- W1993051142 creator A5029692039 @default.
- W1993051142 creator A5051095926 @default.
- W1993051142 creator A5068729684 @default.
- W1993051142 creator A5077486807 @default.
- W1993051142 date "2002-09-01" @default.
- W1993051142 modified "2023-09-27" @default.
- W1993051142 title "Low Dose Intraarterial Thrombolysis with Tissue Plasminogen Activator: Does It Deliver as Promised?" @default.
- W1993051142 cites W1964753262 @default.
- W1993051142 cites W2022176054 @default.
- W1993051142 cites W2026833080 @default.
- W1993051142 cites W2029379525 @default.
- W1993051142 cites W2050361340 @default.
- W1993051142 cites W2060691994 @default.
- W1993051142 cites W4234638057 @default.
- W1993051142 cites W2100157993 @default.
- W1993051142 doi "https://doi.org/10.1177/153857440203600504" @default.
- W1993051142 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12244423" @default.
- W1993051142 hasPublicationYear "2002" @default.
- W1993051142 type Work @default.
- W1993051142 sameAs 1993051142 @default.
- W1993051142 citedByCount "5" @default.
- W1993051142 countsByYear W19930511422018 @default.
- W1993051142 crossrefType "journal-article" @default.
- W1993051142 hasAuthorship W1993051142A5003141413 @default.
- W1993051142 hasAuthorship W1993051142A5013092596 @default.
- W1993051142 hasAuthorship W1993051142A5018276827 @default.
- W1993051142 hasAuthorship W1993051142A5024320307 @default.
- W1993051142 hasAuthorship W1993051142A5029276776 @default.
- W1993051142 hasAuthorship W1993051142A5029692039 @default.
- W1993051142 hasAuthorship W1993051142A5051095926 @default.
- W1993051142 hasAuthorship W1993051142A5068729684 @default.
- W1993051142 hasAuthorship W1993051142A5077486807 @default.
- W1993051142 hasConcept C126322002 @default.
- W1993051142 hasConcept C141071460 @default.
- W1993051142 hasConcept C2776268601 @default.
- W1993051142 hasConcept C2776336681 @default.
- W1993051142 hasConcept C2776572282 @default.
- W1993051142 hasConcept C2779581417 @default.
- W1993051142 hasConcept C2780868729 @default.
- W1993051142 hasConcept C2909817843 @default.
- W1993051142 hasConcept C500558357 @default.
- W1993051142 hasConcept C71924100 @default.
- W1993051142 hasConceptScore W1993051142C126322002 @default.
- W1993051142 hasConceptScore W1993051142C141071460 @default.
- W1993051142 hasConceptScore W1993051142C2776268601 @default.
- W1993051142 hasConceptScore W1993051142C2776336681 @default.
- W1993051142 hasConceptScore W1993051142C2776572282 @default.
- W1993051142 hasConceptScore W1993051142C2779581417 @default.
- W1993051142 hasConceptScore W1993051142C2780868729 @default.
- W1993051142 hasConceptScore W1993051142C2909817843 @default.
- W1993051142 hasConceptScore W1993051142C500558357 @default.
- W1993051142 hasConceptScore W1993051142C71924100 @default.
- W1993051142 hasIssue "5" @default.
- W1993051142 hasLocation W19930511421 @default.
- W1993051142 hasLocation W19930511422 @default.
- W1993051142 hasOpenAccess W1993051142 @default.
- W1993051142 hasPrimaryLocation W19930511421 @default.
- W1993051142 hasRelatedWork W1966793441 @default.
- W1993051142 hasRelatedWork W2016436602 @default.
- W1993051142 hasRelatedWork W2037399775 @default.
- W1993051142 hasRelatedWork W2043777610 @default.
- W1993051142 hasRelatedWork W2056808173 @default.
- W1993051142 hasRelatedWork W2063587198 @default.
- W1993051142 hasRelatedWork W2073343691 @default.
- W1993051142 hasRelatedWork W2083772654 @default.
- W1993051142 hasRelatedWork W2086388125 @default.
- W1993051142 hasRelatedWork W2089237765 @default.
- W1993051142 hasRelatedWork W2090782984 @default.
- W1993051142 hasRelatedWork W2101786402 @default.
- W1993051142 hasRelatedWork W2113428678 @default.
- W1993051142 hasRelatedWork W2142840265 @default.
- W1993051142 hasRelatedWork W2149789266 @default.
- W1993051142 hasRelatedWork W2164638196 @default.
- W1993051142 hasRelatedWork W2393684470 @default.
- W1993051142 hasRelatedWork W2426646657 @default.
- W1993051142 hasRelatedWork W2441359378 @default.
- W1993051142 hasRelatedWork W1969468074 @default.
- W1993051142 hasVolume "36" @default.
- W1993051142 isParatext "false" @default.
- W1993051142 isRetracted "false" @default.
- W1993051142 magId "1993051142" @default.
- W1993051142 workType "article" @default.