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- W1993055164 abstract "Glutathione (GSH) interacts both chemically and enzymatically with fusarin C, a mutagenic metabolite produced by Fusarium moniliforme. The chemical reaction, which is pH-dependent, results in the formation of both fusarin A and a compound that lacks the 2-pyrrolidone moiety thereby suggesting an interaction at the C-13–C-14 epoxide. Enzymatic interaction of fusarin C with GSH also appears to occur at this site as fusarins A and D, which lack the epoxide, do not serve as substrates for GSH-S-transferases. The interaction of GSH with fusarin C appears to be an important deactivation step which could explain the lack of carcinogenicity observed for fusarin C in rats." @default.
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- W1993055164 date "1988-05-01" @default.
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- W1993055164 title "The chemical and enzymatic interaction of glutathione with the fungal metabolite, fusarin C" @default.
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- W1993055164 doi "https://doi.org/10.1016/0027-5107(88)90247-3" @default.
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