Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993103699> ?p ?o ?g. }
Showing items 1 to 90 of
90
with 100 items per page.
- W1993103699 endingPage "127" @default.
- W1993103699 startingPage "115" @default.
- W1993103699 abstract "The bioassay of body fluids experiment is designed to evaluate the biochemical adaptation resulting from extended exposure to space flight environment by identifying changes in hormonal and associated fluid and electrolyte parameters reflected in the blood and urine of the participating crewmen. The combined stresses of space flight include weightlessness, acceleration, confinement, restraint, long-term maintenance of high levels of performance, and possible desynchronosis. Endocrine measurements to assess the physiological cost of these stresses have been considered from two aspects. Fluid and electrolyte balance have been correlated with weight loss, changes in the excretion of aldosterone and vasopressin and fluid compartments. The second area involves the estimation of the physiological cost of maintaining a given level of performance during space flight by analysis of urinary catecholamines and cortisol. Inter-individual variability was demonstrated in most experimental indices measured; however, constant patterns have emerged which include: body weight change; increases in plasma renin activity; elevations in urinary catecholamines, ADH, aldosterone and cortisol concentrations. Plasma cortisol decreases in immediate postflight samples with subsequent increase in 24-hour urines. The measured changes are consistent with the prediction that a relative increase in thoracic blood volume upon transition to the zero-gravity environment is interpreted as a true volume expansion resulting in an osmotic diuresis. This diuresis in association with other factors ultimately results in a reduction in intravascular volume, leading to an increase in renin and a secondary aldosteronism. Once these compensatory mechanisms are effective in reestablishing positive water balance, the crewmen are considered to be essentially adapted to the null-gravity environment. Although the physiological cost of this adaptation must reflect the electrolyte deficit and perhaps other factors, it is assumed that the compensated state is adequate for the demands of the environment; however, this new homeostatic set is not believed to be without physiological cost and could, except with proper precautions, reduce the functional reserve of exposed individuals." @default.
- W1993103699 created "2016-06-24" @default.
- W1993103699 creator A5025991983 @default.
- W1993103699 creator A5067466563 @default.
- W1993103699 date "1975-01-01" @default.
- W1993103699 modified "2023-09-26" @default.
- W1993103699 title "Endocrine responses in long-duration manned space flight" @default.
- W1993103699 cites W1983740357 @default.
- W1993103699 cites W2016078659 @default.
- W1993103699 cites W2044963066 @default.
- W1993103699 cites W2054225948 @default.
- W1993103699 cites W3200838173 @default.
- W1993103699 cites W562116595 @default.
- W1993103699 doi "https://doi.org/10.1016/0094-5765(75)90048-x" @default.
- W1993103699 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11841088" @default.
- W1993103699 hasPublicationYear "1975" @default.
- W1993103699 type Work @default.
- W1993103699 sameAs 1993103699 @default.
- W1993103699 citedByCount "13" @default.
- W1993103699 countsByYear W19931036992014 @default.
- W1993103699 countsByYear W19931036992015 @default.
- W1993103699 countsByYear W19931036992016 @default.
- W1993103699 countsByYear W19931036992017 @default.
- W1993103699 crossrefType "journal-article" @default.
- W1993103699 hasAuthorship W1993103699A5025991983 @default.
- W1993103699 hasAuthorship W1993103699A5067466563 @default.
- W1993103699 hasConcept C103888896 @default.
- W1993103699 hasConcept C121332964 @default.
- W1993103699 hasConcept C126322002 @default.
- W1993103699 hasConcept C1276947 @default.
- W1993103699 hasConcept C134018914 @default.
- W1993103699 hasConcept C138976137 @default.
- W1993103699 hasConcept C178853913 @default.
- W1993103699 hasConcept C185592680 @default.
- W1993103699 hasConcept C195646399 @default.
- W1993103699 hasConcept C198710026 @default.
- W1993103699 hasConcept C2776370428 @default.
- W1993103699 hasConcept C2776735168 @default.
- W1993103699 hasConcept C2778525890 @default.
- W1993103699 hasConcept C2779547328 @default.
- W1993103699 hasConcept C2780091579 @default.
- W1993103699 hasConcept C37557685 @default.
- W1993103699 hasConcept C37752432 @default.
- W1993103699 hasConcept C46699223 @default.
- W1993103699 hasConcept C71315377 @default.
- W1993103699 hasConcept C71924100 @default.
- W1993103699 hasConcept C84393581 @default.
- W1993103699 hasConceptScore W1993103699C103888896 @default.
- W1993103699 hasConceptScore W1993103699C121332964 @default.
- W1993103699 hasConceptScore W1993103699C126322002 @default.
- W1993103699 hasConceptScore W1993103699C1276947 @default.
- W1993103699 hasConceptScore W1993103699C134018914 @default.
- W1993103699 hasConceptScore W1993103699C138976137 @default.
- W1993103699 hasConceptScore W1993103699C178853913 @default.
- W1993103699 hasConceptScore W1993103699C185592680 @default.
- W1993103699 hasConceptScore W1993103699C195646399 @default.
- W1993103699 hasConceptScore W1993103699C198710026 @default.
- W1993103699 hasConceptScore W1993103699C2776370428 @default.
- W1993103699 hasConceptScore W1993103699C2776735168 @default.
- W1993103699 hasConceptScore W1993103699C2778525890 @default.
- W1993103699 hasConceptScore W1993103699C2779547328 @default.
- W1993103699 hasConceptScore W1993103699C2780091579 @default.
- W1993103699 hasConceptScore W1993103699C37557685 @default.
- W1993103699 hasConceptScore W1993103699C37752432 @default.
- W1993103699 hasConceptScore W1993103699C46699223 @default.
- W1993103699 hasConceptScore W1993103699C71315377 @default.
- W1993103699 hasConceptScore W1993103699C71924100 @default.
- W1993103699 hasConceptScore W1993103699C84393581 @default.
- W1993103699 hasIssue "1-2" @default.
- W1993103699 hasLocation W19931036991 @default.
- W1993103699 hasLocation W19931036992 @default.
- W1993103699 hasOpenAccess W1993103699 @default.
- W1993103699 hasPrimaryLocation W19931036991 @default.
- W1993103699 hasRelatedWork W1985396042 @default.
- W1993103699 hasRelatedWork W1991185913 @default.
- W1993103699 hasRelatedWork W1993103699 @default.
- W1993103699 hasRelatedWork W2005975386 @default.
- W1993103699 hasRelatedWork W2020160417 @default.
- W1993103699 hasRelatedWork W2021479380 @default.
- W1993103699 hasRelatedWork W2047608102 @default.
- W1993103699 hasRelatedWork W2138319999 @default.
- W1993103699 hasRelatedWork W2463592634 @default.
- W1993103699 hasRelatedWork W71134282 @default.
- W1993103699 hasVolume "2" @default.
- W1993103699 isParatext "false" @default.
- W1993103699 isRetracted "false" @default.
- W1993103699 magId "1993103699" @default.
- W1993103699 workType "article" @default.