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- W1993145280 abstract "A novel, efficient and diastereoselective procedure was developed for the gram-scale synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT), a selective MT2melatonin receptor antagonist. The synthetic strategy involved the conversion of 4-phenyl-2-tetralone to enamide followed by diastereoselective reduction affording cis-4-P-PDOT in good yield. The mechanism of the reduction step was explored by employing deuterated reagents." @default.
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- W1993145280 date "2008-01-01" @default.
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- W1993145280 title "An improved synthesis of cis-4-phenyl-2-propionamidotetralin (4-P-PDOT): a selective MT<sub>2</sub>melatonin receptor antagonist" @default.
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- W1993145280 doi "https://doi.org/10.1039/b713904g" @default.
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