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• W1993164047 abstract "The <i>Mus musculus </i>and <i>Rattus norvegicus </i>genomes have been extensively studied, yet despite the emergence of <i>Peromyscus maniculatus</i> as an NIH model for genome sequencing and biomedical research much remains unknown about the genome organization of Peromyscines. Contrary to their phylogenetic relationship, the genomes of <i>Rattus</i> and <i>Peromyscus</i> appear more similar at the gross karyotypic level than either does to <i>Mus. </i>We set out to define the chromosome homologies between <i>Peromyscus, Mus </i>and<i> Rattus</i>. Reciprocal cross-species chromosome painting and G-band homology assignments were used to delineate the conserved chromosome homology map between <i>P. maniculatus</i> and <i>M. musculus</i>. These data show that each species has undergone extensive chromosome rearrangements since they last shared a common ancestor 25 million years ago (mya). This analysis coupled with an inferred homology map with <i>Rattus </i>revealed a high level of chromosome conservation between <i>Rattus </i>and <i>Peromyscus</i> and indicated that the chromosomes of <i>Mus </i>are highly derived." @default.
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• W1993164047 date "2008-01-01" @default.
• W1993164047 modified "2023-09-26" @default.
• W1993164047 title "<i>Peromyscus maniculatus</i> – <i>Mus musculus </i>chromosome homology map derived from reciprocal cross species chromosome painting" @default.
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• W1993164047 doi "https://doi.org/10.1159/000138900" @default.
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