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• W1993225158 abstract "Rizell S, Kjellberg H, Dietz W, Norén JG, Lundgren T. Altered inorganic composition of dental enamel and dentin in primary teeth from girls with Turner syndrome . Eur J Oral Sci 2010; 118: 183–190. © 2010 The Authors. Journal compilation © 2010 Eur J Oral Sci In Turner syndrome (TS) one X‐chromosome is missing or defective. The amelogenin gene, located on the X‐chromosome, plays a key role during the formation of dental enamel. The aim of this study was to find support for the hypothesis that impaired expression of the X‐chromosome influences mineral incorporation during amelogenesis and, indirectly, during dentinogenesis. Primary tooth enamel and dentin from girls with TS were analysed and compared with the enamel and dentin of primary teeth from healthy girls. Qualitative and quantitative changes in the composition of TS enamel were found, in addition to morphological differences. Higher frequencies of subsurface lesions and rod‐free zones were seen in TS enamel using polarized light microscopy. Similarly, scanning electron microscopy showed that the enamel rods from TS teeth were of atypical sizes and directions. Using X‐ray microanalysis, high levels of calcium and phosphorus, and low levels of carbon, were found in both TS enamel and dentin. Using microradiography, a lower degree of mineralization was found in TS enamel. Rule induction analysis was performed to identify characteristic element patterns for TS. Low values of carbon were the most critical attributes for the outcome TS. The conclusion was that impaired expression of the X‐chromosome has an impact on dental hard tissue formation." @default.
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• W1993225158 date "2010-03-11" @default.
• W1993225158 modified "2023-10-16" @default.
• W1993225158 title "Altered inorganic composition of dental enamel and dentin in primary teeth from girls with Turner syndrome" @default.
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• W1993225158 doi "https://doi.org/10.1111/j.1600-0722.2010.00718.x" @default.
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