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- W1993242536 abstract "A simple, specific and selective method for the simultaneous determination of zolpidem and zopiclone in human plasma is described. After a liquid-liquid extraction, the extract is injected into a capillary gas chromatograph with an OV-1 fused-silica column coupled to a nitrogen-phosphorus detector. The detection limits are 1 and 2 ng/ml for zolpidem and zopiclone, respectivelly. The methood described is reproducible and linear over a range of concentrations, rendering it suitable for use for pharmacokinetic studies or toxicological evaluations. Absolute identification of the chromatographed compounds is accomplished by gas chromatography-mass spectrometry in both electron-impact and positive-ion chemical ionisation modes." @default.
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- W1993242536 date "1996-01-01" @default.
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- W1993242536 title "Simultaneous determination of zolpidem and zopiclone in human plasma by gas chromatography-nitrogen-phosphorus detection" @default.
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- W1993242536 doi "https://doi.org/10.1016/0378-4347(95)00311-8" @default.
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