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- W1993246571 abstract "3 alpha-Hydroxysteroid dehydrogenase is a cytosolic, monomeric, NADPH-dependent oxidoreductase which reduces 3-keto-5-dihydrosteroids to their tetrahydro products. We present here the first partial amino acid sequence data for the human liver enzyme and show these sequences to be identical to the deduced amino acid sequence for human hepatic chlordecone reductase. In addition, these two enzymes exhibit similar substrate and cofactor specificities and immunological reactivity. The results suggest that the natural substrates for chlordecone reductase are 3-keto-5-dihydrosteroids and that these two proteins may be identical." @default.
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- W1993246571 date "1992-09-01" @default.
- W1993246571 modified "2023-09-27" @default.
- W1993246571 title "Human hepatic 3α-hydroxysteroid dehydrogenase: Possible identity with human hepatic chlordecone reductase" @default.
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- W1993246571 doi "https://doi.org/10.1016/0006-291x(92)91260-w" @default.
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