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• W1993291301 abstract "Electrolyte composition of cisternal CSF was measured during 4 hours of respiratory and metabolic acid-base disturbance in anesthetized dogs. Three groups of dogs were studied: (1), isocapnic metabolic alkalosis; (2), acute respiratory acidosis; and (3), combined respiratory acidosis and metabolic alkalosis. Cisternal CSF [K+] remained unchanged despite significant changes in plasma [K+], PCO2 and [HCO3-]; suggesting that mechanisms involved in regulation of CSF [K+] continue to operate normally under such conditions. Cisternal [Na+] and osmolality remained unchanged with almost identical reciprocal equimolar changes in CSF concentration of Cl- and HCO3- during the acid-base disorders studied. The regulatory mechanisms involved in this Cl- -HCO3- exchange may be different in different acid-base disorders, but since CSF [Na+] is kept constant, CSF [HCO3-] in any acid-base disorder equals the difference between CSF [Na+] and CSF [Cl-]." @default.
• W1993291301 created "2016-06-24" @default.
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• W1993291301 date "1981-08-01" @default.
• W1993291301 modified "2023-09-25" @default.
• W1993291301 title "Electrolyte composition of cerebrospinal fluid in acute acid-base disorders" @default.
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• W1993291301 doi "https://doi.org/10.1016/0034-5687(81)90056-6" @default.
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