Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993323237> ?p ?o ?g. }
Showing items 1 to 100 of
100
with 100 items per page.
- W1993323237 endingPage "450" @default.
- W1993323237 startingPage "445" @default.
- W1993323237 abstract "In three infants with neonatal lacticacidaemia, a deficiency in the E1 (pyruvate dehydrogenase) component of the pyruvate dehydrogenase complex was demonstrated in skin fibroblast cultures. Residual activities of the pyruvate dehydrogenase complex in the activated state were 1.6%, 3.9% and 18.8% of control values, respectively. Immunoprecipitation of extracts of cultures skin fibroblasts grown on 35S-methionine with anti-pyruvate dehydrogenase complex antibody revealed an abnormality in the E1 alpha-component of these three patients when visualised after sodium dodecyl sulphate/polyacrylamide gel electrophoresis. This component appeared to have a slightly lower molecular weight than did this protein from control cell strains. Cell strains from other patients with a deficiency of the pyruvate dehydrogenase complex did not exhibit this defect. Three patients also showed dysmorphism and developmental abnormalities of the central nervous system." @default.
- W1993323237 created "2016-06-24" @default.
- W1993323237 creator A5030215961 @default.
- W1993323237 creator A5037431253 @default.
- W1993323237 creator A5069076893 @default.
- W1993323237 creator A5081410784 @default.
- W1993323237 creator A5087981512 @default.
- W1993323237 creator A5091389858 @default.
- W1993323237 date "1986-02-01" @default.
- W1993323237 modified "2023-09-27" @default.
- W1993323237 title "Lacticacidaemia due to pyruvate dehydrogenase deficiency, with evidence of protein polymorphism in the ?-subunit of the enzyme" @default.
- W1993323237 cites W1510598783 @default.
- W1993323237 cites W1915827411 @default.
- W1993323237 cites W1965401751 @default.
- W1993323237 cites W1975831985 @default.
- W1993323237 cites W1985262723 @default.
- W1993323237 cites W1985522920 @default.
- W1993323237 cites W1998490400 @default.
- W1993323237 cites W2018347313 @default.
- W1993323237 cites W2028210595 @default.
- W1993323237 cites W2042478578 @default.
- W1993323237 cites W2055679053 @default.
- W1993323237 cites W2057714231 @default.
- W1993323237 cites W2071978262 @default.
- W1993323237 cites W2075311640 @default.
- W1993323237 cites W2163302837 @default.
- W1993323237 cites W2199233259 @default.
- W1993323237 cites W2250532506 @default.
- W1993323237 cites W324270611 @default.
- W1993323237 doi "https://doi.org/10.1007/bf00441736" @default.
- W1993323237 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3082638" @default.
- W1993323237 hasPublicationYear "1986" @default.
- W1993323237 type Work @default.
- W1993323237 sameAs 1993323237 @default.
- W1993323237 citedByCount "38" @default.
- W1993323237 countsByYear W19933232372012 @default.
- W1993323237 countsByYear W19933232372014 @default.
- W1993323237 crossrefType "journal-article" @default.
- W1993323237 hasAuthorship W1993323237A5030215961 @default.
- W1993323237 hasAuthorship W1993323237A5037431253 @default.
- W1993323237 hasAuthorship W1993323237A5069076893 @default.
- W1993323237 hasAuthorship W1993323237A5081410784 @default.
- W1993323237 hasAuthorship W1993323237A5087981512 @default.
- W1993323237 hasAuthorship W1993323237A5091389858 @default.
- W1993323237 hasBestOaLocation W19933232372 @default.
- W1993323237 hasConcept C104292427 @default.
- W1993323237 hasConcept C104317684 @default.
- W1993323237 hasConcept C126093377 @default.
- W1993323237 hasConcept C151325109 @default.
- W1993323237 hasConcept C153911025 @default.
- W1993323237 hasConcept C179402230 @default.
- W1993323237 hasConcept C181199279 @default.
- W1993323237 hasConcept C190098323 @default.
- W1993323237 hasConcept C2776317432 @default.
- W1993323237 hasConcept C2780912031 @default.
- W1993323237 hasConcept C515207424 @default.
- W1993323237 hasConcept C55493867 @default.
- W1993323237 hasConcept C71924100 @default.
- W1993323237 hasConcept C86803240 @default.
- W1993323237 hasConcept C88099638 @default.
- W1993323237 hasConcept C9506865 @default.
- W1993323237 hasConceptScore W1993323237C104292427 @default.
- W1993323237 hasConceptScore W1993323237C104317684 @default.
- W1993323237 hasConceptScore W1993323237C126093377 @default.
- W1993323237 hasConceptScore W1993323237C151325109 @default.
- W1993323237 hasConceptScore W1993323237C153911025 @default.
- W1993323237 hasConceptScore W1993323237C179402230 @default.
- W1993323237 hasConceptScore W1993323237C181199279 @default.
- W1993323237 hasConceptScore W1993323237C190098323 @default.
- W1993323237 hasConceptScore W1993323237C2776317432 @default.
- W1993323237 hasConceptScore W1993323237C2780912031 @default.
- W1993323237 hasConceptScore W1993323237C515207424 @default.
- W1993323237 hasConceptScore W1993323237C55493867 @default.
- W1993323237 hasConceptScore W1993323237C71924100 @default.
- W1993323237 hasConceptScore W1993323237C86803240 @default.
- W1993323237 hasConceptScore W1993323237C88099638 @default.
- W1993323237 hasConceptScore W1993323237C9506865 @default.
- W1993323237 hasIssue "5" @default.
- W1993323237 hasLocation W19933232371 @default.
- W1993323237 hasLocation W19933232372 @default.
- W1993323237 hasLocation W19933232373 @default.
- W1993323237 hasOpenAccess W1993323237 @default.
- W1993323237 hasPrimaryLocation W19933232371 @default.
- W1993323237 hasRelatedWork W1661091665 @default.
- W1993323237 hasRelatedWork W1779131763 @default.
- W1993323237 hasRelatedWork W1795884996 @default.
- W1993323237 hasRelatedWork W1884642153 @default.
- W1993323237 hasRelatedWork W2008710440 @default.
- W1993323237 hasRelatedWork W2015269539 @default.
- W1993323237 hasRelatedWork W204747089 @default.
- W1993323237 hasRelatedWork W2052296365 @default.
- W1993323237 hasRelatedWork W2468520735 @default.
- W1993323237 hasRelatedWork W2739062483 @default.
- W1993323237 hasVolume "144" @default.
- W1993323237 isParatext "false" @default.
- W1993323237 isRetracted "false" @default.
- W1993323237 magId "1993323237" @default.
- W1993323237 workType "article" @default.