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• W1993376998 endingPage "63" @default.
• W1993376998 startingPage "55" @default.
• W1993376998 abstract "Abstract AMP‐activated protein kinase (AMPK) is a cellular energy sensor that is conserved in eukaryotes. Elevated AMP/ATP ratio activates AMPK, which inhibits energy‐consuming processes and activates energy‐producing processes to restore the energy homeostasis inside the cell. AMPK activators, metformin and thiazolidinediones, are used for the treatment of type II diabetes. Recently, reports have indicated that AMPK may also be a beneficial target for cancer treatment. Cancer cells have characteristic metabolic changes different from normal cells and, being a key metabolic regulator, AMPK may regulate the switch. AMPK may act to inhibit tumorigenesis through regulation of cell growth, cell proliferation, autophagy, stress responses and cell polarity." @default.
• W1993376998 created "2016-06-24" @default.
• W1993376998 creator A5037621688 @default.
• W1993376998 creator A5083214596 @default.
• W1993376998 date "2009-04-01" @default.
• W1993376998 modified "2023-09-29" @default.
• W1993376998 title "AMP-activated protein kinase and cancer" @default.
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• W1993376998 doi "https://doi.org/10.1111/j.1748-1716.2009.01980.x" @default.

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