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- W1993403939 abstract "Chemokines play an important role in orchestrating cell recruitment and localization in both physiological and pathological conditions. More than 44 ligands have been identified in the human genome. A significantly different set of chemokines, however, is found in the mouse genome, suggesting a rapid evolution of the chemokine system in mammalian genomes. Thus, there are lineage and even individual-specific differences in chemokine genes in mammals. Differences in the expression and function between even recently duplicated genes are also evident. In this review, we discuss how evolutionary events such as gene duplication and gene conversion have shaped the diverse arrays of chemokines in mammalian genomes." @default.
- W1993403939 created "2016-06-24" @default.
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- W1993403939 date "2010-08-01" @default.
- W1993403939 modified "2023-09-30" @default.
- W1993403939 title "The evolution of mammalian chemokine genes" @default.
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- W1993403939 doi "https://doi.org/10.1016/j.cytogfr.2010.03.004" @default.
- W1993403939 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20434943" @default.
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