FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993413428> ?p ?o ?g. }

• W1993413428 endingPage "1046" @default.
• W1993413428 startingPage "1038" @default.
• W1993413428 abstract "Cyclosporine (CsA) and prednisone (Pred) are the most widely used drugs for immunosuppression after renal transplantation, but both drugs have marked side effects. Either replacement of CsA by azathioprine (Aza) or withdrawal of prednisone (Pred) resulting in CsA monotherapy can be employed to circumvent the adverse effects in the long run. Both treatment regimens were compared in this prospective randomized trial in patients who were treated with CsA and Pred during the first 3 months after renal transplantation (CsA: n=64, Aza-Pred: n=63, median duration of follow-up: 3.9 years). Estimated graft survival rates at 5 years after transplantation (in patients with a functioning graft at 3 months) were 78% in the CsA group and 87% in the Aza-Pred group. The incidence of a rejection within 3 months after start of steroid withdrawal or conversion from CsA to Aza was 30% and 25%, respectively (NS). At 2 years after transplantation, serum creatinine levels were lower in the Aza-Pred group (126±35 μmol/L) than in the CsA group (180±78 μmol/L; P<0.001). There were no differences in blood pressure or incidence of infections between the treatment groups. Treatment-related costs were measured during the first year after transplantation and were lower in the Aza-Pred group (DFL 40,882±18,895 vs. DFL 53,484±44,828; 1 DFL [Dutch guilder] is about US $0.60; P<0.05). In conclusion, CsA monotherapy and Aza-Pred treatment from 3 months after renal transplantation are comparably effective immunosuppressive treatment regimens, although Aza-Pred therapy results in better graft function. Withdrawal of steroids and replacement of CsA by Aza both carry a substantial risk of rejection. The previously demonstrated cost effectiveness of CsA-containing therapies seems to be limited to the first phase after transplantation. Conversion to Aza-Pred at 3 months after transplantation reduces costs." @default.
• W1993413428 created "2016-06-24" @default.
• W1993413428 creator A5010073289 @default.
• W1993413428 creator A5055928576 @default.
• W1993413428 creator A5090101674 @default.
• W1993413428 date "1996-04-01" @default.
• W1993413428 modified "2023-10-16" @default.
• W1993413428 title "RANDOMIZED, PROSPECTIVE TRIAL OF CYCLOSPORINE MONOTHERAPY VERSUS AZATHIOPRINE-PREDNISONE FROM THREE MONTHS AFTER RENAL TRANSPLANTATION1" @default.
• W1993413428 cites W1550111394 @default.
• W1993413428 cites W1906833341 @default.
• W1993413428 cites W1960912206 @default.
• W1993413428 cites W1976049374 @default.
• W1993413428 cites W1981651266 @default.
• W1993413428 cites W1996494884 @default.
• W1993413428 cites W2004658798 @default.
• W1993413428 cites W2004931181 @default.
• W1993413428 cites W2006382152 @default.
• W1993413428 cites W2010390181 @default.
• W1993413428 cites W2010608641 @default.
• W1993413428 cites W2031569062 @default.
• W1993413428 cites W2045274472 @default.
• W1993413428 cites W2048520205 @default.
• W1993413428 cites W2051143996 @default.
• W1993413428 cites W2052082703 @default.
• W1993413428 cites W2078081445 @default.
• W1993413428 cites W2082239957 @default.
• W1993413428 cites W2082390491 @default.
• W1993413428 cites W2083107662 @default.
• W1993413428 cites W2092762429 @default.
• W1993413428 cites W2093328167 @default.
• W1993413428 cites W2094712929 @default.
• W1993413428 cites W2319735235 @default.
• W1993413428 cites W2324876747 @default.
• W1993413428 cites W2417620455 @default.
• W1993413428 cites W4240718512 @default.
• W1993413428 cites W4252996964 @default.
• W1993413428 cites W4317639304 @default.
• W1993413428 doi "https://doi.org/10.1097/00007890-199604150-00009" @default.
• W1993413428 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8623182" @default.
• W1993413428 hasPublicationYear "1996" @default.
• W1993413428 type Work @default.
• W1993413428 sameAs 1993413428 @default.
• W1993413428 citedByCount "48" @default.
• W1993413428 countsByYear W19934134282012 @default.
• W1993413428 countsByYear W19934134282016 @default.
• W1993413428 countsByYear W19934134282017 @default.
• W1993413428 countsByYear W19934134282020 @default.
• W1993413428 countsByYear W19934134282021 @default.
• W1993413428 countsByYear W19934134282022 @default.
• W1993413428 crossrefType "journal-article" @default.
• W1993413428 hasAuthorship W1993413428A5010073289 @default.
• W1993413428 hasAuthorship W1993413428A5055928576 @default.
• W1993413428 hasAuthorship W1993413428A5090101674 @default.
• W1993413428 hasBestOaLocation W19934134281 @default.
• W1993413428 hasConcept C126322002 @default.
• W1993413428 hasConcept C126894567 @default.
• W1993413428 hasConcept C141071460 @default.
• W1993413428 hasConcept C197934379 @default.
• W1993413428 hasConcept C2776760755 @default.
• W1993413428 hasConcept C2776804153 @default.
• W1993413428 hasConcept C2778720950 @default.
• W1993413428 hasConcept C2779134260 @default.
• W1993413428 hasConcept C2780252810 @default.
• W1993413428 hasConcept C2780303639 @default.
• W1993413428 hasConcept C2780306776 @default.
• W1993413428 hasConcept C2911091166 @default.
• W1993413428 hasConcept C71924100 @default.
• W1993413428 hasConcept C90924648 @default.
• W1993413428 hasConceptScore W1993413428C126322002 @default.
• W1993413428 hasConceptScore W1993413428C126894567 @default.
• W1993413428 hasConceptScore W1993413428C141071460 @default.
• W1993413428 hasConceptScore W1993413428C197934379 @default.
• W1993413428 hasConceptScore W1993413428C2776760755 @default.
• W1993413428 hasConceptScore W1993413428C2776804153 @default.
• W1993413428 hasConceptScore W1993413428C2778720950 @default.
• W1993413428 hasConceptScore W1993413428C2779134260 @default.
• W1993413428 hasConceptScore W1993413428C2780252810 @default.
• W1993413428 hasConceptScore W1993413428C2780303639 @default.
• W1993413428 hasConceptScore W1993413428C2780306776 @default.
• W1993413428 hasConceptScore W1993413428C2911091166 @default.
• W1993413428 hasConceptScore W1993413428C71924100 @default.
• W1993413428 hasConceptScore W1993413428C90924648 @default.
• W1993413428 hasIssue "7" @default.
• W1993413428 hasLocation W19934134281 @default.
• W1993413428 hasLocation W19934134282 @default.
• W1993413428 hasLocation W19934134283 @default.
• W1993413428 hasLocation W19934134284 @default.
• W1993413428 hasOpenAccess W1993413428 @default.
• W1993413428 hasPrimaryLocation W19934134281 @default.
• W1993413428 hasRelatedWork W1486584413 @default.
• W1993413428 hasRelatedWork W1504336519 @default.
• W1993413428 hasRelatedWork W2037116344 @default.
• W1993413428 hasRelatedWork W2043631135 @default.
• W1993413428 hasRelatedWork W2056932738 @default.
• W1993413428 hasRelatedWork W2087086071 @default.
• W1993413428 hasRelatedWork W2142657464 @default.
• W1993413428 hasRelatedWork W2410398696 @default.
• W1993413428 hasRelatedWork W2427645694 @default.

• next