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- W1993413730 abstract "Curcumin dissolved in polyethyleneglycol PEG 400 was added to serum samples spiked with several photolabile drugs. The samples were exposed to light and analyzed for the content of undecomposed drug by means of HPLC. Curcumin had a slight stabilizing effect on furosemide and clonazepam in serum. The photostability of nifedipine in serum, however, was clearly improved, with a 6-fold increase in half-life by addition of curcumin. The photochemical degradation of nifedipine followed first-order kinetics independent of addition of curcumin. Addition of curcumin to serum samples in clinical laboratories may improve the results of nifedipine determination." @default.
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- W1993413730 date "1988-01-01" @default.
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- W1993413730 title "Studies on curcumin and curcuminoids. XL stabilization of photolabile drugs in serum samples by addition of curcumin" @default.
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- W1993413730 doi "https://doi.org/10.1016/0378-5173(88)90138-x" @default.
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