FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993442099> ?p ?o ?g. }

• W1993442099 endingPage "491" @default.
• W1993442099 startingPage "486" @default.
• W1993442099 abstract "Anaemia causes significant morbidity in children with Plasmodium falciparum malaria, but the mechanism(s) are unclear. During malarial infection, increased reactive oxygen species (ROS) are generated that may contribute to erythrocyte damage and anaemia. This study measured the concentrations of alpha-tocopherol in plasma and erythrocyte membranes, and the percentage polyunsaturated fatty acid composition (%PUFA) (an indirect marker of ROS damage) in erythrocyte membranes in children with severe P. falciparum malaria from Kilifi, Kenya, and asymptomatic children from the same district. Malarial subjects were stratified into complicated malaria and malaria anaemia. Results demonstrated significant reductions in erythrocyte membrane alpha-tocopherol concentration (1.63 +/- 0.16 versus 3.38 +/- 0.18 micromol/mg protein; P < 0.001) and total %PUFA (30.7 +/- 0.49 versus 32.8 +/- 0.44% P < 0.005) for the malarial subjects (non-stratified) compared with controls. Malarial subjects showed a significant positive correlation between membrane alpha-tocopherol and haemoglobin concentrations (P < 0.005 r = 0.63 complicated malaria group; P < 0.05 r = 0.36 non-stratified data). There were no significant differences in plasma alpha-tocopherol concentration between malaria patients and controls. In conclusion, malarial infection may be associated with oxidative damage and reduced alpha-tocopherol reserve in the erythrocyte membrane, suggesting that local antioxidant depletion may contribute to erythrocyte loss in severe malaria. Erythrocyte membrane alpha-tocopherol appeared a better indicator of ROS exposure than plasma." @default.
• W1993442099 created "2016-06-24" @default.
• W1993442099 creator A5014291864 @default.
• W1993442099 creator A5015092104 @default.
• W1993442099 creator A5072332085 @default.
• W1993442099 creator A5074423609 @default.
• W1993442099 creator A5080540974 @default.
• W1993442099 creator A5091761108 @default.
• W1993442099 date "2001-05-01" @default.
• W1993442099 modified "2023-10-18" @default.
• W1993442099 title "Oxidative stress and erythrocyte damage in Kenyan children with severe<i>Plasmodium falciparum</i>malaria" @default.
• W1993442099 cites W139815902 @default.
• W1993442099 cites W1787204411 @default.
• W1993442099 cites W1876118699 @default.
• W1993442099 cites W1946263363 @default.
• W1993442099 cites W1970564042 @default.
• W1993442099 cites W1974283996 @default.
• W1993442099 cites W1983281349 @default.
• W1993442099 cites W1991926823 @default.
• W1993442099 cites W2001255173 @default.
• W1993442099 cites W2001698428 @default.
• W1993442099 cites W2003731854 @default.
• W1993442099 cites W2005631952 @default.
• W1993442099 cites W2006124405 @default.
• W1993442099 cites W2008162971 @default.
• W1993442099 cites W2026304182 @default.
• W1993442099 cites W2028849594 @default.
• W1993442099 cites W2034174843 @default.
• W1993442099 cites W2034467957 @default.
• W1993442099 cites W2066224179 @default.
• W1993442099 cites W2081219185 @default.
• W1993442099 cites W2089772634 @default.
• W1993442099 cites W2091162467 @default.
• W1993442099 cites W2093594054 @default.
• W1993442099 cites W2099637695 @default.
• W1993442099 cites W2128609534 @default.
• W1993442099 cites W2140802223 @default.
• W1993442099 cites W2211467290 @default.
• W1993442099 cites W2322213143 @default.
• W1993442099 cites W2339321981 @default.
• W1993442099 cites W4232534952 @default.
• W1993442099 doi "https://doi.org/10.1046/j.1365-2141.2001.02758.x" @default.
• W1993442099 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11380421" @default.
• W1993442099 hasPublicationYear "2001" @default.
• W1993442099 type Work @default.
• W1993442099 sameAs 1993442099 @default.
• W1993442099 citedByCount "113" @default.
• W1993442099 countsByYear W19934420992012 @default.
• W1993442099 countsByYear W19934420992013 @default.
• W1993442099 countsByYear W19934420992014 @default.
• W1993442099 countsByYear W19934420992015 @default.
• W1993442099 countsByYear W19934420992016 @default.
• W1993442099 countsByYear W19934420992017 @default.
• W1993442099 countsByYear W19934420992018 @default.
• W1993442099 countsByYear W19934420992019 @default.
• W1993442099 countsByYear W19934420992021 @default.
• W1993442099 countsByYear W19934420992022 @default.
• W1993442099 countsByYear W19934420992023 @default.
• W1993442099 crossrefType "journal-article" @default.
• W1993442099 hasAuthorship W1993442099A5014291864 @default.
• W1993442099 hasAuthorship W1993442099A5015092104 @default.
• W1993442099 hasAuthorship W1993442099A5072332085 @default.
• W1993442099 hasAuthorship W1993442099A5074423609 @default.
• W1993442099 hasAuthorship W1993442099A5080540974 @default.
• W1993442099 hasAuthorship W1993442099A5091761108 @default.
• W1993442099 hasBestOaLocation W19934420991 @default.
• W1993442099 hasConcept C126322002 @default.
• W1993442099 hasConcept C203014093 @default.
• W1993442099 hasConcept C2776151105 @default.
• W1993442099 hasConcept C2776557347 @default.
• W1993442099 hasConcept C2777551382 @default.
• W1993442099 hasConcept C2777910003 @default.
• W1993442099 hasConcept C2778004101 @default.
• W1993442099 hasConcept C2778048844 @default.
• W1993442099 hasConcept C2778371730 @default.
• W1993442099 hasConcept C2781449162 @default.
• W1993442099 hasConcept C2993443003 @default.
• W1993442099 hasConcept C41625074 @default.
• W1993442099 hasConcept C42407357 @default.
• W1993442099 hasConcept C55493867 @default.
• W1993442099 hasConcept C71924100 @default.
• W1993442099 hasConcept C86803240 @default.
• W1993442099 hasConceptScore W1993442099C126322002 @default.
• W1993442099 hasConceptScore W1993442099C203014093 @default.
• W1993442099 hasConceptScore W1993442099C2776151105 @default.
• W1993442099 hasConceptScore W1993442099C2776557347 @default.
• W1993442099 hasConceptScore W1993442099C2777551382 @default.
• W1993442099 hasConceptScore W1993442099C2777910003 @default.
• W1993442099 hasConceptScore W1993442099C2778004101 @default.
• W1993442099 hasConceptScore W1993442099C2778048844 @default.
• W1993442099 hasConceptScore W1993442099C2778371730 @default.
• W1993442099 hasConceptScore W1993442099C2781449162 @default.
• W1993442099 hasConceptScore W1993442099C2993443003 @default.
• W1993442099 hasConceptScore W1993442099C41625074 @default.
• W1993442099 hasConceptScore W1993442099C42407357 @default.
• W1993442099 hasConceptScore W1993442099C55493867 @default.
• W1993442099 hasConceptScore W1993442099C71924100 @default.
• W1993442099 hasConceptScore W1993442099C86803240 @default.

• next