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- W1993471567 abstract "The metabolism of neostigmine by fractions of rat liver has been investigated using 14C neostigmine. It has been shown that the drug is metabolized to 3-hydroxy-phenyltrimethylammonium by the microsome fraction of rat liver and that the metabolism is completely inhibited by SKF 525-A. These results support the evidence from in vivo studies that the metabolism of neostigmine is inhibited by SKF 525-A. It is suggested that the clinical effects of neostigmine may be influenced by concurrent treatment with other drugs which are metabolized by the liver." @default.
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- W1993471567 date "1968-01-01" @default.
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- W1993471567 title "Metabolism of neostigmine in vitro" @default.
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- W1993471567 doi "https://doi.org/10.1016/0006-2952(68)90151-2" @default.
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