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- W1993534443 abstract "We explored the feasibility of using carbon-13 ((13)C) magnetic resonance imaging ((13)C-MRI) to depict (13)C-labeled methionine-enriched gliomas at 4.7 tesla. We transplanted 2 types of glioma cells separately to 2 subcutaneous tissue sites on the backs of mice weighing 15 to 20 g. After confirming tumor growth, we used (13)C-MRI and (1)H-MRI to scan 4 mice that had been administered (13)C-labeled methionine and 2 control mice. (13)C-MRI of all 4 transplanted mice administered with (13)C-labeled methionine revealed 2 areas of hyperintensity that corresponded to the tumor sites on (1)H-MR images, but no such areas were visualized in transplanted controls. Our data suggest that (13)C-MRI can show the accumulation of (13)C-labeled tracer by gliomas." @default.
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- W1993534443 date "2011-01-01" @default.
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- W1993534443 title "13C MR Imaging of Methionine-rich Gliomas at 4.7T: A Pilot Study" @default.
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- W1993534443 doi "https://doi.org/10.2463/mrms.10.139" @default.
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