FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993592018> ?p ?o ?g. }

• W1993592018 endingPage "348" @default.
• W1993592018 startingPage "341" @default.
• W1993592018 abstract "Neovascularization in the retinopathy of prematurity (ROP) mouse eye is a self-limiting phenomenon. Free endostatin is known to be anti-angiogenic. In this study, we identified the localization of endostatin-like protein (ELP) sequences and investigated their possible role in this process. ROP was induced in C57Bl/6 mice and the eyes observed 1-11 days after termination of high oxygen supply (P13-P21). Sagittal sections and retinal flatmounts were double-stained with antibodies against a protein-sequence of endostatin, vascular endothelial growth factor (VEGF), lectin, and smooth-muscle alpha actin. The fluorescence was visualized by traditional and confocal microscopy. Intense staining for VEGF in the inner retina was limited to the early stages of neovascularization and diminished at P19-P21. In contrast, staining for ELPs appeared at P15 around the newly formed vessels and remained even after degeneration of their endothelial cells. Staining of the inner retinal vasculature for ELPs was restricted to P17-P19, the known maximum of the neovascular response. Outer retinal vessels did not show presence of ELPs at any time. Our study demonstrates that ELPs, absent at the beginning of neovascular sprouting, increases with the amount of neovascularization and thus, varies reciprocally to VEGF in the time period investigated. ELPs remain during the regression of the vessels and might therefore play an important role in the self-limiting process of ROP neovascularization." @default.
• W1993592018 created "2016-06-24" @default.
• W1993592018 creator A5006167710 @default.
• W1993592018 creator A5036730920 @default.
• W1993592018 creator A5086306497 @default.
• W1993592018 creator A5086377835 @default.
• W1993592018 date "2006-02-01" @default.
• W1993592018 modified "2023-10-18" @default.
• W1993592018 title "Proteins with an endostatin-like domain in a mouse model of oxygen-induced retinopathy" @default.
• W1993592018 cites W1967004211 @default.
• W1993592018 cites W1968431199 @default.
• W1993592018 cites W1970142098 @default.
• W1993592018 cites W1970895236 @default.
• W1993592018 cites W1989029150 @default.
• W1993592018 cites W1994014733 @default.
• W1993592018 cites W2027971364 @default.
• W1993592018 cites W2030470138 @default.
• W1993592018 cites W2033887376 @default.
• W1993592018 cites W2037348124 @default.
• W1993592018 cites W2042604169 @default.
• W1993592018 cites W2057652578 @default.
• W1993592018 cites W2058873146 @default.
• W1993592018 cites W2063844610 @default.
• W1993592018 cites W2064147974 @default.
• W1993592018 cites W2065504792 @default.
• W1993592018 cites W2075086348 @default.
• W1993592018 cites W2077545882 @default.
• W1993592018 cites W2080857015 @default.
• W1993592018 cites W2085396553 @default.
• W1993592018 cites W2088255586 @default.
• W1993592018 cites W2089026133 @default.
• W1993592018 cites W2131798870 @default.
• W1993592018 cites W2146155292 @default.
• W1993592018 cites W2161968188 @default.
• W1993592018 cites W2166765368 @default.
• W1993592018 cites W2169882258 @default.
• W1993592018 cites W2299715745 @default.
• W1993592018 doi "https://doi.org/10.1016/j.exer.2005.07.005" @default.
• W1993592018 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16122735" @default.
• W1993592018 hasPublicationYear "2006" @default.
• W1993592018 type Work @default.
• W1993592018 sameAs 1993592018 @default.
• W1993592018 citedByCount "17" @default.
• W1993592018 countsByYear W19935920182012 @default.
• W1993592018 countsByYear W19935920182015 @default.
• W1993592018 countsByYear W19935920182018 @default.
• W1993592018 countsByYear W19935920182021 @default.
• W1993592018 countsByYear W19935920182023 @default.
• W1993592018 crossrefType "journal-article" @default.
• W1993592018 hasAuthorship W1993592018A5006167710 @default.
• W1993592018 hasAuthorship W1993592018A5036730920 @default.
• W1993592018 hasAuthorship W1993592018A5086306497 @default.
• W1993592018 hasAuthorship W1993592018A5086377835 @default.
• W1993592018 hasConcept C118487528 @default.
• W1993592018 hasConcept C142724271 @default.
• W1993592018 hasConcept C146285616 @default.
• W1993592018 hasConcept C167734588 @default.
• W1993592018 hasConcept C169760540 @default.
• W1993592018 hasConcept C2776403814 @default.
• W1993592018 hasConcept C2777025900 @default.
• W1993592018 hasConcept C2777093970 @default.
• W1993592018 hasConcept C2778271429 @default.
• W1993592018 hasConcept C2778376644 @default.
• W1993592018 hasConcept C2779234561 @default.
• W1993592018 hasConcept C2779918416 @default.
• W1993592018 hasConcept C2780394083 @default.
• W1993592018 hasConcept C2780827179 @default.
• W1993592018 hasConcept C502942594 @default.
• W1993592018 hasConcept C54355233 @default.
• W1993592018 hasConcept C71924100 @default.
• W1993592018 hasConcept C74864618 @default.
• W1993592018 hasConcept C75920679 @default.
• W1993592018 hasConcept C86803240 @default.
• W1993592018 hasConceptScore W1993592018C118487528 @default.
• W1993592018 hasConceptScore W1993592018C142724271 @default.
• W1993592018 hasConceptScore W1993592018C146285616 @default.
• W1993592018 hasConceptScore W1993592018C167734588 @default.
• W1993592018 hasConceptScore W1993592018C169760540 @default.
• W1993592018 hasConceptScore W1993592018C2776403814 @default.
• W1993592018 hasConceptScore W1993592018C2777025900 @default.
• W1993592018 hasConceptScore W1993592018C2777093970 @default.
• W1993592018 hasConceptScore W1993592018C2778271429 @default.
• W1993592018 hasConceptScore W1993592018C2778376644 @default.
• W1993592018 hasConceptScore W1993592018C2779234561 @default.
• W1993592018 hasConceptScore W1993592018C2779918416 @default.
• W1993592018 hasConceptScore W1993592018C2780394083 @default.
• W1993592018 hasConceptScore W1993592018C2780827179 @default.
• W1993592018 hasConceptScore W1993592018C502942594 @default.
• W1993592018 hasConceptScore W1993592018C54355233 @default.
• W1993592018 hasConceptScore W1993592018C71924100 @default.
• W1993592018 hasConceptScore W1993592018C74864618 @default.
• W1993592018 hasConceptScore W1993592018C75920679 @default.
• W1993592018 hasConceptScore W1993592018C86803240 @default.
• W1993592018 hasIssue "2" @default.
• W1993592018 hasLocation W19935920181 @default.
• W1993592018 hasLocation W19935920182 @default.
• W1993592018 hasOpenAccess W1993592018 @default.
• W1993592018 hasPrimaryLocation W19935920181 @default.

• next