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• W1993595102 abstract "A simple and readily manoeuverable method for preparing immuno-magnetic liposomes that indigenously contain binding sites for attaching other molecules like antibodies on their exterior surface is described. In this method magnetic unilamellar vesicles are prepared from a mixture of phosphatidylcholine, cholesterol, small amounts of a linear chain aldehyde and colloidal particles of magnetic iron oxide, using a reverse phase evaporation technique. The aldehyde (dedecanal) molecules align themselves among the lipid molecules in the bilayer with their aldehyde groups exposed to the aqueous phase, allowing straight attachment of antibody molecules (human-antimouse IgG-FITC in this case) in one single step. The success of this approach is confirmed by fluorescence microscopy as well as binding of the resulting immuno-magnetic liposomes to their corresponding target cells." @default.
• W1993595102 created "2016-06-24" @default.
• W1993595102 creator A5033477318 @default.
• W1993595102 creator A5048085857 @default.
• W1993595102 date "2001-03-01" @default.
• W1993595102 modified "2023-10-14" @default.
• W1993595102 title "A simple method for preparation of immuno-magnetic liposomes" @default.
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• W1993595102 doi "https://doi.org/10.1016/s0378-5173(00)00667-0" @default.
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