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- W1993605220 abstract "Analysis of optically active compounds in complex samples is often based on chiral chromatography or capillary electrophoresis in order to separate the enantiomers. This requires a chiral reagent, when using conventional chromatography, or an expensive chiral column, or a chiral selector, when using capillary electrophoresis. The type of column, reagent, or additive depends highly on the compound to be analysed. A simple and generally applicable method is using a conventional HPLC column coupled to a CD detector. Separation of enantiomers is not required, as they can be identified by a positive or negative peak. A racemate does not produce a peak; neither does an optically inactive compound. The application of HPLC-CD for the identification of pharmacologically active compounds, such as dexamphetamine, 5-hydroxytryptophan, (−)-huperzine A, and interferon, as standards, in registered drugs, in falsifications, and in food supplements is described." @default.
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- W1993605220 date "2003-08-01" @default.
- W1993605220 modified "2023-09-26" @default.
- W1993605220 title "Analysis of optically active compounds using conventional chromatography with a circular dichroism detector" @default.
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- W1993605220 doi "https://doi.org/10.1016/s0731-7085(03)00192-4" @default.
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