Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993609207> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W1993609207 endingPage "198" @default.
- W1993609207 startingPage "193" @default.
- W1993609207 abstract "This study summarises the results of four different chemicals evaluated for induction of micronuclei (MN) in L5178Y tk(+/-) cells in the absence of cytochalasin B. All four chemicals (the tubulin polymerisation inhibitor Colchicine, Diethylstilboestrol which inhibits both tubulin polymersation as well as depolymerisation, the cross-linking agent Mitomycin C and Cyclophosphamide which requires metabolism to form the ultimate mutagen) showed biologically and statistically significant induction in MN frequency compared to concurrent controls. Irrespective of whether the measure of cytotoxicity was based on relative cell count (RCC), relative increase in cell count (RICC) or relative population doubling (RPD), micronucleus induction was observed at or below the targeted toxicity of 55±5%. Therefore, all measures of cytotoxicity in the absence of cytochalasin B proved to be equally acceptable to select the top-dose without missing micronucleation activity for any of the four compounds." @default.
- W1993609207 created "2016-06-24" @default.
- W1993609207 creator A5010863061 @default.
- W1993609207 creator A5070283755 @default.
- W1993609207 date "2010-10-01" @default.
- W1993609207 modified "2023-10-01" @default.
- W1993609207 title "Comparison of different cytotoxicity measures for the in vitro micronucleus test (MNVit) in L5178Y tk+/− cells: Summary of 4 compounds (Mitomycin C, Cyclophosphamide, Colchicine and Diethylstilboestrol) with clastogenic and aneugenic mode of action" @default.
- W1993609207 cites W156463007 @default.
- W1993609207 cites W1965724734 @default.
- W1993609207 cites W1967331918 @default.
- W1993609207 cites W1996619663 @default.
- W1993609207 cites W2010737160 @default.
- W1993609207 cites W2056257023 @default.
- W1993609207 cites W2154917705 @default.
- W1993609207 cites W2575095704 @default.
- W1993609207 doi "https://doi.org/10.1016/j.mrgentox.2010.03.018" @default.
- W1993609207 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20362070" @default.
- W1993609207 hasPublicationYear "2010" @default.
- W1993609207 type Work @default.
- W1993609207 sameAs 1993609207 @default.
- W1993609207 citedByCount "12" @default.
- W1993609207 countsByYear W19936092072012 @default.
- W1993609207 countsByYear W19936092072013 @default.
- W1993609207 countsByYear W19936092072015 @default.
- W1993609207 countsByYear W19936092072016 @default.
- W1993609207 countsByYear W19936092072018 @default.
- W1993609207 countsByYear W19936092072019 @default.
- W1993609207 countsByYear W19936092072020 @default.
- W1993609207 crossrefType "journal-article" @default.
- W1993609207 hasAuthorship W1993609207A5010863061 @default.
- W1993609207 hasAuthorship W1993609207A5070283755 @default.
- W1993609207 hasConcept C109316439 @default.
- W1993609207 hasConcept C114246631 @default.
- W1993609207 hasConcept C141710004 @default.
- W1993609207 hasConcept C153911025 @default.
- W1993609207 hasConcept C178790620 @default.
- W1993609207 hasConcept C185592680 @default.
- W1993609207 hasConcept C202751555 @default.
- W1993609207 hasConcept C2776636253 @default.
- W1993609207 hasConcept C2776639595 @default.
- W1993609207 hasConcept C2778959862 @default.
- W1993609207 hasConcept C2779012151 @default.
- W1993609207 hasConcept C2779338040 @default.
- W1993609207 hasConcept C2908647359 @default.
- W1993609207 hasConcept C29730261 @default.
- W1993609207 hasConcept C33070731 @default.
- W1993609207 hasConcept C36681516 @default.
- W1993609207 hasConcept C45080847 @default.
- W1993609207 hasConcept C54355233 @default.
- W1993609207 hasConcept C71924100 @default.
- W1993609207 hasConcept C86803240 @default.
- W1993609207 hasConcept C98274493 @default.
- W1993609207 hasConcept C99454951 @default.
- W1993609207 hasConceptScore W1993609207C109316439 @default.
- W1993609207 hasConceptScore W1993609207C114246631 @default.
- W1993609207 hasConceptScore W1993609207C141710004 @default.
- W1993609207 hasConceptScore W1993609207C153911025 @default.
- W1993609207 hasConceptScore W1993609207C178790620 @default.
- W1993609207 hasConceptScore W1993609207C185592680 @default.
- W1993609207 hasConceptScore W1993609207C202751555 @default.
- W1993609207 hasConceptScore W1993609207C2776636253 @default.
- W1993609207 hasConceptScore W1993609207C2776639595 @default.
- W1993609207 hasConceptScore W1993609207C2778959862 @default.
- W1993609207 hasConceptScore W1993609207C2779012151 @default.
- W1993609207 hasConceptScore W1993609207C2779338040 @default.
- W1993609207 hasConceptScore W1993609207C2908647359 @default.
- W1993609207 hasConceptScore W1993609207C29730261 @default.
- W1993609207 hasConceptScore W1993609207C33070731 @default.
- W1993609207 hasConceptScore W1993609207C36681516 @default.
- W1993609207 hasConceptScore W1993609207C45080847 @default.
- W1993609207 hasConceptScore W1993609207C54355233 @default.
- W1993609207 hasConceptScore W1993609207C71924100 @default.
- W1993609207 hasConceptScore W1993609207C86803240 @default.
- W1993609207 hasConceptScore W1993609207C98274493 @default.
- W1993609207 hasConceptScore W1993609207C99454951 @default.
- W1993609207 hasIssue "2" @default.
- W1993609207 hasLocation W19936092071 @default.
- W1993609207 hasLocation W19936092072 @default.
- W1993609207 hasOpenAccess W1993609207 @default.
- W1993609207 hasPrimaryLocation W19936092071 @default.
- W1993609207 hasRelatedWork W1993609207 @default.
- W1993609207 hasRelatedWork W2005012224 @default.
- W1993609207 hasRelatedWork W2037269272 @default.
- W1993609207 hasRelatedWork W2038270678 @default.
- W1993609207 hasRelatedWork W2091355127 @default.
- W1993609207 hasRelatedWork W2094406616 @default.
- W1993609207 hasRelatedWork W2165941540 @default.
- W1993609207 hasRelatedWork W2474447810 @default.
- W1993609207 hasRelatedWork W4248146848 @default.
- W1993609207 hasRelatedWork W800071576 @default.
- W1993609207 hasVolume "702" @default.
- W1993609207 isParatext "false" @default.
- W1993609207 isRetracted "false" @default.
- W1993609207 magId "1993609207" @default.
- W1993609207 workType "article" @default.