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• W1993622445 endingPage "54" @default.
• W1993622445 startingPage "30" @default.
• W1993622445 abstract "FTER ACUTE MYOCARDIAL INFARCTION, the clinical course of approximately 12 per cent of patients is complicated by manifestations of circulatory shock. 1-4 With supportive treatment, including oxygen breathing and analgesic drugs, fewer than 1 of 5 patients survive. ~ The initial enthusiasm for vasopressor drugs, introduced 15 years ago, has been sustained by reports that the survival rate was doubled after introduction of these drugs2 Yet, others find no definitive evidence that these drugs have improved survival. 2,7's Since our understanding of both mechanisms and treatment of acute myocardial infarction and its complications is still very meager, convention rather than proved efficacy guides much of current practice in this field. After greater understanding of mechanisms is achieved, the rational basis for treatment will undoubtedly be greatly improved. Even modest improvement would profoundly alter the dismal outlook. A decrease in mortality of but 15 per cent would essentially double the number of survivors. The conscientious clinician, however, is alerted not only to the potential benefits of newer drugs and other innovations of management but he is properly suspicious that innovations are likely to entail greater risks before their ultimate value is established. With these considerations in mind, we reviewed experimental and clinical data on the treatment of shock complicating myocardial infarction, aided by the results of our own investigations in the University of Southern California Shock Research Unit at the Los Angeles County General Hospital. 9 This contribution is intended as a guide or, preferably, a resource to aid in the planning of bedside treatment." @default.
• W1993622445 created "2016-06-24" @default.
• W1993622445 creator A5003125230 @default.
• W1993622445 creator A5065139009 @default.
• W1993622445 date "1967-07-01" @default.
• W1993622445 modified "2023-10-16" @default.
• W1993622445 title "The treatment of shock complicating acute myocardial infarction" @default.
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