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- W1993623563 abstract "Some of the metabolic changes associated with the administration of l-glutamic acid and l-arginine to patients with hyperammoniemia have been studied. The infusion of glutamate was accompanied by a fall and a subsequent post-infusion rise in blood ammonia, by a rise and subsequent post-infusion fall in glutamine and alpha-ketoglutaric acid and, on occasions, by a fall in citric acid. The infusion of arginine hydrochloride was not attended by any immediate significant fall in blood ammonia, and only occasionally by a rise in blood urea nitrogen. No changes were observed in the other parameters which were studied. The biochemical and clinical implications of these observations have been discussed. Some of the metabolic changes associated with the administration of l-glutamic acid and l-arginine to patients with hyperammoniemia have been studied. The infusion of glutamate was accompanied by a fall and a subsequent post-infusion rise in blood ammonia, by a rise and subsequent post-infusion fall in glutamine and alpha-ketoglutaric acid and, on occasions, by a fall in citric acid. The infusion of arginine hydrochloride was not attended by any immediate significant fall in blood ammonia, and only occasionally by a rise in blood urea nitrogen. No changes were observed in the other parameters which were studied. The biochemical and clinical implications of these observations have been discussed." @default.
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- W1993623563 title "Biochemical changes associated with the administration of glutamic acid and arginine to patients with hyperammonemia" @default.
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- W1993623563 doi "https://doi.org/10.1016/s0022-4804(61)80036-x" @default.
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