FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993665150> ?p ?o ?g. }

• W1993665150 endingPage "535" @default.
• W1993665150 startingPage "523" @default.
• W1993665150 abstract "Membrane fusion plays a central role in the synaptic vesicle cycle. While many of the pre- and postfusion events have been investigated at room temperature, few researchers have investigated these processes at more physiologically relevant temperatures. We have used autaptic cultures of hippocampal neurons to investigate changes in the size and refilling rate of the readily releasable pool (RRP) of synaptic vesicles brought about by an increase in temperature from 25 to 35 degrees C. We have also examined temperature-dependent changes in spontaneous and action potential (AP)-evoked release as well as the fraction of the RRP that is released during an AP. Although we found a threefold increase in the refilling rate of the RRP at the higher temperature, there was no apparent change in the size of the RRP with increased temperature. Moreover, we observed a slight but significant decrease in the quanta released during an AP. This increased refilling rate and decreased release probability resulted in a reduction of both the degree and time course of synaptic depression during high frequency stimulation at the higher temperature. This reduction in synaptic depression was accompanied by an increased maintenance of the synchronous component of release during high frequency stimulation. These findings indicate that the dynamics of vesicular supply and release in hippocampal neurons at room temperature are significantly different at near physiological temperatures and could affect our present understanding of the way in which individual neurons and networks of neurons process information." @default.
• W1993665150 created "2016-06-24" @default.
• W1993665150 creator A5019763780 @default.
• W1993665150 creator A5071224695 @default.
• W1993665150 date "2002-03-01" @default.
• W1993665150 modified "2023-09-23" @default.
• W1993665150 title "The effects of temperature on vesicular supply and release in autaptic cultures of rat and mouse hippocampal neurons" @default.
• W1993665150 cites W1528038969 @default.
• W1993665150 cites W1536357320 @default.
• W1993665150 cites W1554693724 @default.
• W1993665150 cites W1567391514 @default.
• W1993665150 cites W1622189158 @default.
• W1993665150 cites W1690684669 @default.
• W1993665150 cites W1877594537 @default.
• W1993665150 cites W1927867726 @default.
• W1993665150 cites W1927932324 @default.
• W1993665150 cites W1967580786 @default.
• W1993665150 cites W1967804600 @default.
• W1993665150 cites W1983245247 @default.
• W1993665150 cites W1990057321 @default.
• W1993665150 cites W1993373202 @default.
• W1993665150 cites W2001520037 @default.
• W1993665150 cites W2002426597 @default.
• W1993665150 cites W2014114637 @default.
• W1993665150 cites W2016016372 @default.
• W1993665150 cites W2018867131 @default.
• W1993665150 cites W2019106988 @default.
• W1993665150 cites W2022104262 @default.
• W1993665150 cites W2029413329 @default.
• W1993665150 cites W2037593266 @default.
• W1993665150 cites W2038359286 @default.
• W1993665150 cites W2038556096 @default.
• W1993665150 cites W2044309585 @default.
• W1993665150 cites W2051620676 @default.
• W1993665150 cites W2055374196 @default.
• W1993665150 cites W2055454610 @default.
• W1993665150 cites W2065359945 @default.
• W1993665150 cites W2069536209 @default.
• W1993665150 cites W2071358119 @default.
• W1993665150 cites W2072389508 @default.
• W1993665150 cites W2075268251 @default.
• W1993665150 cites W2076324460 @default.
• W1993665150 cites W2080778713 @default.
• W1993665150 cites W2083809146 @default.
• W1993665150 cites W2086459954 @default.
• W1993665150 cites W2102492718 @default.
• W1993665150 cites W2105829350 @default.
• W1993665150 cites W2114745427 @default.
• W1993665150 cites W2131338541 @default.
• W1993665150 cites W2143494304 @default.
• W1993665150 cites W2147119735 @default.
• W1993665150 cites W2151522879 @default.
• W1993665150 cites W2159353177 @default.
• W1993665150 cites W2162668311 @default.
• W1993665150 cites W2166291087 @default.
• W1993665150 cites W2205834389 @default.
• W1993665150 cites W2246103349 @default.
• W1993665150 cites W4300875606 @default.
• W1993665150 cites W4321429291 @default.
• W1993665150 doi "https://doi.org/10.1113/jphysiol.2001.013277" @default.
• W1993665150 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2290147" @default.
• W1993665150 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11882684" @default.
• W1993665150 hasPublicationYear "2002" @default.
• W1993665150 type Work @default.
• W1993665150 sameAs 1993665150 @default.
• W1993665150 citedByCount "151" @default.
• W1993665150 countsByYear W19936651502012 @default.
• W1993665150 countsByYear W19936651502013 @default.
• W1993665150 countsByYear W19936651502014 @default.
• W1993665150 countsByYear W19936651502015 @default.
• W1993665150 countsByYear W19936651502016 @default.
• W1993665150 countsByYear W19936651502017 @default.
• W1993665150 countsByYear W19936651502018 @default.
• W1993665150 countsByYear W19936651502019 @default.
• W1993665150 countsByYear W19936651502020 @default.
• W1993665150 countsByYear W19936651502021 @default.
• W1993665150 countsByYear W19936651502022 @default.
• W1993665150 crossrefType "journal-article" @default.
• W1993665150 hasAuthorship W1993665150A5019763780 @default.
• W1993665150 hasAuthorship W1993665150A5071224695 @default.
• W1993665150 hasBestOaLocation W19936651501 @default.
• W1993665150 hasConcept C12554922 @default.
• W1993665150 hasConcept C127445978 @default.
• W1993665150 hasConcept C130316041 @default.
• W1993665150 hasConcept C148762608 @default.
• W1993665150 hasConcept C148785051 @default.
• W1993665150 hasConcept C169760540 @default.
• W1993665150 hasConcept C185263204 @default.
• W1993665150 hasConcept C185592680 @default.
• W1993665150 hasConcept C24998067 @default.
• W1993665150 hasConcept C41625074 @default.
• W1993665150 hasConcept C55493867 @default.
• W1993665150 hasConcept C86803240 @default.
• W1993665150 hasConcept C95444343 @default.
• W1993665150 hasConceptScore W1993665150C12554922 @default.
• W1993665150 hasConceptScore W1993665150C127445978 @default.
• W1993665150 hasConceptScore W1993665150C130316041 @default.
• W1993665150 hasConceptScore W1993665150C148762608 @default.

• next