FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993669291> ?p ?o ?g. }

• W1993669291 endingPage "1843" @default.
• W1993669291 startingPage "1837" @default.
• W1993669291 abstract "Some experimental transplant-tolerance models have shown that the presence of regulatory T cells within grafts is important for the development of tolerance (Tol). METHODS.: To determine if the presence of regulatory T cells correlates with graft acceptance in living-donor liver-transplantation tolerance, the expression of Foxp3 mRNA and the presence of CD4, CD8, and Foxp3 cells were quantified in biopsies from tolerant recipients by real-time polymerase chain reaction and by immunohistochemistry and immunofluorescent staining (Gr-Tol). The results were compared with biopsies from the recipients on maintenance immunosuppression (Gr-IS), grafts removed because of chronic rejection (Gr-CR), or normal liver (Gr-NL).The expression of Foxp3 mRNA in Gr-Tol was higher than that in Gr-IS (P=0.07) and Gr-NL (P<0.0001), but equivalent to that in Gr-CR. In Gr-Tol, Foxp3 cells were detectable within the clustered CD4 and CD8 cells in the portal areas. Ninety-two percent of those Foxp3 cells were CD4, whereas 8% were CD8. The number of Foxp3 cells was significantly increased in Gr-Tol, compared with that in Gr-IS (P<0.05), although the number of CD4 or CD8 cells did not differ between the two. Foxp3 cells were hardly detectable in Gr-CR or -NL.This is the first report showing that CD4Foxp3 cells are present within grafts in a subset of tolerant patients after human liver transplantation. A prospective study is needed to elucidate whether the assessment of intragraft expression of Foxp3 protein, but not Foxp3 mRNA, can aid the identification of living-donor liver-transplantation recipients who can successfully withdraw IS." @default.
• W1993669291 created "2016-06-24" @default.
• W1993669291 creator A5001484839 @default.
• W1993669291 creator A5009335876 @default.
• W1993669291 creator A5025764166 @default.
• W1993669291 creator A5028439535 @default.
• W1993669291 creator A5029400756 @default.
• W1993669291 creator A5050506872 @default.
• W1993669291 creator A5060002817 @default.
• W1993669291 creator A5072168969 @default.
• W1993669291 creator A5072214554 @default.
• W1993669291 creator A5087819106 @default.
• W1993669291 date "2008-12-27" @default.
• W1993669291 modified "2023-10-18" @default.
• W1993669291 title "The Presence of Foxp3 Expressing T Cells Within Grafts of Tolerant Human Liver Transplant Recipients" @default.
• W1993669291 cites W1605277044 @default.
• W1993669291 cites W1963619444 @default.
• W1993669291 cites W1967257073 @default.
• W1993669291 cites W1977836556 @default.
• W1993669291 cites W1982144289 @default.
• W1993669291 cites W1983019708 @default.
• W1993669291 cites W1984909066 @default.
• W1993669291 cites W1989928855 @default.
• W1993669291 cites W2002726823 @default.
• W1993669291 cites W2018008269 @default.
• W1993669291 cites W2022174161 @default.
• W1993669291 cites W2024729349 @default.
• W1993669291 cites W2025446247 @default.
• W1993669291 cites W2026942934 @default.
• W1993669291 cites W2059467273 @default.
• W1993669291 cites W2083619823 @default.
• W1993669291 cites W2100989466 @default.
• W1993669291 cites W2114412297 @default.
• W1993669291 cites W2121250603 @default.
• W1993669291 cites W2135054826 @default.
• W1993669291 cites W2155984955 @default.
• W1993669291 cites W2168846334 @default.
• W1993669291 cites W2170949754 @default.
• W1993669291 cites W2792966232 @default.
• W1993669291 doi "https://doi.org/10.1097/tp.0b013e31818febc4" @default.
• W1993669291 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19104431" @default.
• W1993669291 hasPublicationYear "2008" @default.
• W1993669291 type Work @default.
• W1993669291 sameAs 1993669291 @default.
• W1993669291 citedByCount "117" @default.
• W1993669291 countsByYear W19936692912012 @default.
• W1993669291 countsByYear W19936692912013 @default.
• W1993669291 countsByYear W19936692912014 @default.
• W1993669291 countsByYear W19936692912015 @default.
• W1993669291 countsByYear W19936692912016 @default.
• W1993669291 countsByYear W19936692912017 @default.
• W1993669291 countsByYear W19936692912018 @default.
• W1993669291 countsByYear W19936692912019 @default.
• W1993669291 countsByYear W19936692912020 @default.
• W1993669291 countsByYear W19936692912021 @default.
• W1993669291 countsByYear W19936692912022 @default.
• W1993669291 crossrefType "journal-article" @default.
• W1993669291 hasAuthorship W1993669291A5001484839 @default.
• W1993669291 hasAuthorship W1993669291A5009335876 @default.
• W1993669291 hasAuthorship W1993669291A5025764166 @default.
• W1993669291 hasAuthorship W1993669291A5028439535 @default.
• W1993669291 hasAuthorship W1993669291A5029400756 @default.
• W1993669291 hasAuthorship W1993669291A5050506872 @default.
• W1993669291 hasAuthorship W1993669291A5060002817 @default.
• W1993669291 hasAuthorship W1993669291A5072168969 @default.
• W1993669291 hasAuthorship W1993669291A5072214554 @default.
• W1993669291 hasAuthorship W1993669291A5087819106 @default.
• W1993669291 hasBestOaLocation W19936692911 @default.
• W1993669291 hasConcept C126322002 @default.
• W1993669291 hasConcept C153911025 @default.
• W1993669291 hasConcept C16685009 @default.
• W1993669291 hasConcept C167672396 @default.
• W1993669291 hasConcept C203014093 @default.
• W1993669291 hasConcept C2777702733 @default.
• W1993669291 hasConcept C2779609443 @default.
• W1993669291 hasConcept C2779727006 @default.
• W1993669291 hasConcept C2780252810 @default.
• W1993669291 hasConcept C2911091166 @default.
• W1993669291 hasConcept C71924100 @default.
• W1993669291 hasConcept C86803240 @default.
• W1993669291 hasConcept C8891405 @default.
• W1993669291 hasConceptScore W1993669291C126322002 @default.
• W1993669291 hasConceptScore W1993669291C153911025 @default.
• W1993669291 hasConceptScore W1993669291C16685009 @default.
• W1993669291 hasConceptScore W1993669291C167672396 @default.
• W1993669291 hasConceptScore W1993669291C203014093 @default.
• W1993669291 hasConceptScore W1993669291C2777702733 @default.
• W1993669291 hasConceptScore W1993669291C2779609443 @default.
• W1993669291 hasConceptScore W1993669291C2779727006 @default.
• W1993669291 hasConceptScore W1993669291C2780252810 @default.
• W1993669291 hasConceptScore W1993669291C2911091166 @default.
• W1993669291 hasConceptScore W1993669291C71924100 @default.
• W1993669291 hasConceptScore W1993669291C86803240 @default.
• W1993669291 hasConceptScore W1993669291C8891405 @default.
• W1993669291 hasIssue "12" @default.
• W1993669291 hasLocation W19936692911 @default.
• W1993669291 hasLocation W19936692912 @default.
• W1993669291 hasLocation W19936692913 @default.

• next