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- W1993689916 abstract "Prolonged infusion of dexmedetomidine, an α(2)-adrenoreceptor agonist anesthetic used in the intensive care unit, produces a withdrawal syndrome of sympathetic over-activity, characterized by tachycardia, hypertension and agitation, but there is no recommended standard treatment for this syndrome. We describe two patients with a clinical diagnosis of acute dexmedetomidine withdrawal and its management with oral clonidine. We utilized the principle of managing acute drug withdrawal with longer acting medications. These two cases demonstrated the benefit of using oral, longer acting clonidine to manage acute withdrawal from shorter-acting, intravenous dexmedetomidine." @default.
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- W1993689916 date "2012-10-30" @default.
- W1993689916 modified "2023-09-26" @default.
- W1993689916 title "Two cases of acute dexmedetomidine withdrawal syndrome following prolonged infusion in the intensive care unit" @default.
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- W1993689916 doi "https://doi.org/10.1177/0960327112454896" @default.
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