FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993746543> ?p ?o ?g. }

• W1993746543 endingPage "33" @default.
• W1993746543 startingPage "25" @default.
• W1993746543 abstract "<i>Background/Aim:</i> We examined the influence of chronic treatment with angiotensin-(1–7) [Ang-(1–7)] on renox (renal NADPH oxidase, NOX-4) and the development of renal dysfunction in streptozotocin-treated spontaneously hypertensive rats (diabetic SHR). <i>Methods:</i>Mean arterial pressure, urinary protein and vascular responsiveness of the isolated renal artery to vasoactive agonists were studied in vehicle- or Ang-(1–7)-treated SHR and diabetic SHR. <i>Results:</i> Ang-(1–7) decreased the elevated levels of renal NADPH oxidase (NOX) activity and attenuated the activation of NOX-4 gene expression in the diabetic SHR kidney. Ang-(1–7) treatment increased sodium excretion but did not affect mean arterial pressure in diabetic SHR. There was a significant increase in urinary protein (266 ± 22 mg/24 h) in the diabetic compared to control SHR (112 ± 13 mg/24 h) and treatment of diabetic SHR with Ang-(1–7) reduced the degree of proteinuria (185 ± 23 mg/24 h, p < 0.05). Ang-(1–7) treatment also attenuated the diabetes-induced increase in renal vascular responsiveness to endothelin-1, norepinephrine, and angiotensin II in SHR, but significantly increased the vasodilation of the renal artery of SHR and diabetic SHR to the vasodilator agonists. <i>Conclusion:</i> These results suggest that treatment with Ang-(1–7) constitutes a potential therapeutic strategy to alleviate NOX-mediated oxidative stress and to reduce renal dysfunction in diabetic hypertensive rats." @default.
• W1993746543 created "2016-06-24" @default.
• W1993746543 creator A5004121123 @default.
• W1993746543 creator A5012210618 @default.
• W1993746543 creator A5034603627 @default.
• W1993746543 creator A5062833068 @default.
• W1993746543 creator A5072715305 @default.
• W1993746543 creator A5089284052 @default.
• W1993746543 date "2007-09-20" @default.
• W1993746543 modified "2023-09-23" @default.
• W1993746543 title "Angiotensin-(1–7) Prevents Activation of NADPH Oxidase and Renal Vascular Dysfunction in Diabetic Hypertensive Rats" @default.
• W1993746543 cites W1573931014 @default.
• W1993746543 cites W1976611127 @default.
• W1993746543 cites W1977257762 @default.
• W1993746543 cites W1977424733 @default.
• W1993746543 cites W1983424304 @default.
• W1993746543 cites W1986255254 @default.
• W1993746543 cites W1989975509 @default.
• W1993746543 cites W2000625731 @default.
• W1993746543 cites W2007082781 @default.
• W1993746543 cites W2019063477 @default.
• W1993746543 cites W2020834404 @default.
• W1993746543 cites W2025458248 @default.
• W1993746543 cites W2025722770 @default.
• W1993746543 cites W2032576629 @default.
• W1993746543 cites W2037778735 @default.
• W1993746543 cites W2041718175 @default.
• W1993746543 cites W2044500356 @default.
• W1993746543 cites W2054960859 @default.
• W1993746543 cites W2060927358 @default.
• W1993746543 cites W2068814987 @default.
• W1993746543 cites W2071594061 @default.
• W1993746543 cites W2082502030 @default.
• W1993746543 cites W2083695720 @default.
• W1993746543 cites W2084555374 @default.
• W1993746543 cites W2089549133 @default.
• W1993746543 cites W2104899725 @default.
• W1993746543 cites W2115933163 @default.
• W1993746543 cites W2132975480 @default.
• W1993746543 cites W2149729817 @default.
• W1993746543 cites W2151150148 @default.
• W1993746543 cites W2152007030 @default.
• W1993746543 cites W2156891309 @default.
• W1993746543 cites W2160316026 @default.
• W1993746543 cites W2163208005 @default.
• W1993746543 cites W2283019668 @default.
• W1993746543 cites W2321747774 @default.
• W1993746543 cites W2414097174 @default.
• W1993746543 doi "https://doi.org/10.1159/000108758" @default.
• W1993746543 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/17890855" @default.
• W1993746543 hasPublicationYear "2007" @default.
• W1993746543 type Work @default.
• W1993746543 sameAs 1993746543 @default.
• W1993746543 citedByCount "177" @default.
• W1993746543 countsByYear W19937465432012 @default.
• W1993746543 countsByYear W19937465432013 @default.
• W1993746543 countsByYear W19937465432014 @default.
• W1993746543 countsByYear W19937465432015 @default.
• W1993746543 countsByYear W19937465432016 @default.
• W1993746543 countsByYear W19937465432017 @default.
• W1993746543 countsByYear W19937465432018 @default.
• W1993746543 countsByYear W19937465432019 @default.
• W1993746543 countsByYear W19937465432020 @default.
• W1993746543 countsByYear W19937465432021 @default.
• W1993746543 countsByYear W19937465432022 @default.
• W1993746543 countsByYear W19937465432023 @default.
• W1993746543 crossrefType "journal-article" @default.
• W1993746543 hasAuthorship W1993746543A5004121123 @default.
• W1993746543 hasAuthorship W1993746543A5012210618 @default.
• W1993746543 hasAuthorship W1993746543A5034603627 @default.
• W1993746543 hasAuthorship W1993746543A5062833068 @default.
• W1993746543 hasAuthorship W1993746543A5072715305 @default.
• W1993746543 hasAuthorship W1993746543A5089284052 @default.
• W1993746543 hasConcept C120770815 @default.
• W1993746543 hasConcept C126322002 @default.
• W1993746543 hasConcept C134018914 @default.
• W1993746543 hasConcept C198710026 @default.
• W1993746543 hasConcept C2776151105 @default.
• W1993746543 hasConcept C2779561371 @default.
• W1993746543 hasConcept C2779719074 @default.
• W1993746543 hasConcept C2780091579 @default.
• W1993746543 hasConcept C2780972559 @default.
• W1993746543 hasConcept C2908929049 @default.
• W1993746543 hasConcept C555293320 @default.
• W1993746543 hasConcept C71924100 @default.
• W1993746543 hasConcept C84393581 @default.
• W1993746543 hasConceptScore W1993746543C120770815 @default.
• W1993746543 hasConceptScore W1993746543C126322002 @default.
• W1993746543 hasConceptScore W1993746543C134018914 @default.
• W1993746543 hasConceptScore W1993746543C198710026 @default.
• W1993746543 hasConceptScore W1993746543C2776151105 @default.
• W1993746543 hasConceptScore W1993746543C2779561371 @default.
• W1993746543 hasConceptScore W1993746543C2779719074 @default.
• W1993746543 hasConceptScore W1993746543C2780091579 @default.
• W1993746543 hasConceptScore W1993746543C2780972559 @default.
• W1993746543 hasConceptScore W1993746543C2908929049 @default.
• W1993746543 hasConceptScore W1993746543C555293320 @default.
• W1993746543 hasConceptScore W1993746543C71924100 @default.

• next