Matches in SemOpenAlex for { <https://semopenalex.org/work/W1993764658> ?p ?o ?g. }
- W1993764658 endingPage "209" @default.
- W1993764658 startingPage "185" @default.
- W1993764658 abstract "Abstract Targeting oxidative stress with inhibiting or boosting the endogenous levels of antioxidants potentially has an outstanding effect in the treatment of oxidative-stress-related diseases. The present work demonstrates the synthesis of quercetin nanoemulsion as one of the potential antioxidants for the treatment of oxidative- stress-related diseases. A quercetin nanoemulsion was prepared using poly(lactic-co-glycolic acid) (PLGA), hyaluronic acid (HA) and emulsifier (Tween-20) through a solvent evaporation technique. The efficiency of the nanoemulsion was evaluated with and without chemical permeation enhancer (CPE). The FT-IR result shows no interaction between quercetin and polymer that proves excellent compatibility. The transdermal delivery ability was evaluated using in vitro release and ex vivo permeation analysis. The transdermal drug-release mechanism was studied by the mathematical model and was found to obey a zero-order, diffusion-controlled mechanism. In vitro toxicity and cell behavior, including cell adhesion, proliferation and cell death of quercetin-nanoemulsion-treated L929 cells, were elucidated by the electrical cell-substrate impedance sensing (ECIS) technique. The produced nanoemulsion showed a high encapsulation efficiency, less toxicity, controlled delivery with enhanced transdermal drug permeation and effective scavenging of free radicals." @default.
- W1993764658 created "2016-06-24" @default.
- W1993764658 creator A5009885710 @default.
- W1993764658 creator A5014936214 @default.
- W1993764658 date "2012-05-11" @default.
- W1993764658 modified "2023-10-18" @default.
- W1993764658 title "A Transdermal Delivery System to Enhance Quercetin Nanoparticle Permeability" @default.
- W1993764658 cites W1964847440 @default.
- W1993764658 cites W1966808384 @default.
- W1993764658 cites W1974654832 @default.
- W1993764658 cites W1976616659 @default.
- W1993764658 cites W1985305155 @default.
- W1993764658 cites W1986329432 @default.
- W1993764658 cites W1988097052 @default.
- W1993764658 cites W1995441472 @default.
- W1993764658 cites W2002102563 @default.
- W1993764658 cites W2006560775 @default.
- W1993764658 cites W2009974403 @default.
- W1993764658 cites W2010908849 @default.
- W1993764658 cites W2012381843 @default.
- W1993764658 cites W2012387037 @default.
- W1993764658 cites W2012671897 @default.
- W1993764658 cites W2014809153 @default.
- W1993764658 cites W2014821488 @default.
- W1993764658 cites W2016711291 @default.
- W1993764658 cites W2016829041 @default.
- W1993764658 cites W2022146849 @default.
- W1993764658 cites W2028673458 @default.
- W1993764658 cites W2043597900 @default.
- W1993764658 cites W2047271327 @default.
- W1993764658 cites W2050764344 @default.
- W1993764658 cites W2051292995 @default.
- W1993764658 cites W2065870072 @default.
- W1993764658 cites W2066142107 @default.
- W1993764658 cites W2069728361 @default.
- W1993764658 cites W2075379234 @default.
- W1993764658 cites W2078862809 @default.
- W1993764658 cites W2079564877 @default.
- W1993764658 cites W2082865634 @default.
- W1993764658 cites W2085911180 @default.
- W1993764658 cites W2087518223 @default.
- W1993764658 cites W2088067817 @default.
- W1993764658 cites W2088294270 @default.
- W1993764658 cites W2090000969 @default.
- W1993764658 cites W2097815597 @default.
- W1993764658 cites W2102051171 @default.
- W1993764658 cites W2109106143 @default.
- W1993764658 cites W2115439624 @default.
- W1993764658 cites W2136388349 @default.
- W1993764658 cites W2155118487 @default.
- W1993764658 cites W2156968573 @default.
- W1993764658 cites W2165749758 @default.
- W1993764658 cites W24682425 @default.
- W1993764658 cites W3023255929 @default.
- W1993764658 doi "https://doi.org/10.1163/156856212x630258" @default.
- W1993764658 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23565597" @default.
- W1993764658 hasPublicationYear "2012" @default.
- W1993764658 type Work @default.
- W1993764658 sameAs 1993764658 @default.
- W1993764658 citedByCount "24" @default.
- W1993764658 countsByYear W19937646582012 @default.
- W1993764658 countsByYear W19937646582013 @default.
- W1993764658 countsByYear W19937646582014 @default.
- W1993764658 countsByYear W19937646582015 @default.
- W1993764658 countsByYear W19937646582016 @default.
- W1993764658 countsByYear W19937646582018 @default.
- W1993764658 countsByYear W19937646582019 @default.
- W1993764658 countsByYear W19937646582020 @default.
- W1993764658 countsByYear W19937646582021 @default.
- W1993764658 countsByYear W19937646582022 @default.
- W1993764658 countsByYear W19937646582023 @default.
- W1993764658 crossrefType "journal-article" @default.
- W1993764658 hasAuthorship W1993764658A5009885710 @default.
- W1993764658 hasAuthorship W1993764658A5014936214 @default.
- W1993764658 hasConcept C185592680 @default.
- W1993764658 hasConcept C202751555 @default.
- W1993764658 hasConcept C205679159 @default.
- W1993764658 hasConcept C2776151105 @default.
- W1993764658 hasConcept C2778004101 @default.
- W1993764658 hasConcept C2780165375 @default.
- W1993764658 hasConcept C2781263971 @default.
- W1993764658 hasConcept C41625074 @default.
- W1993764658 hasConcept C50670333 @default.
- W1993764658 hasConcept C55493867 @default.
- W1993764658 hasConcept C71924100 @default.
- W1993764658 hasConcept C98274493 @default.
- W1993764658 hasConceptScore W1993764658C185592680 @default.
- W1993764658 hasConceptScore W1993764658C202751555 @default.
- W1993764658 hasConceptScore W1993764658C205679159 @default.
- W1993764658 hasConceptScore W1993764658C2776151105 @default.
- W1993764658 hasConceptScore W1993764658C2778004101 @default.
- W1993764658 hasConceptScore W1993764658C2780165375 @default.
- W1993764658 hasConceptScore W1993764658C2781263971 @default.
- W1993764658 hasConceptScore W1993764658C41625074 @default.
- W1993764658 hasConceptScore W1993764658C50670333 @default.
- W1993764658 hasConceptScore W1993764658C55493867 @default.
- W1993764658 hasConceptScore W1993764658C71924100 @default.
- W1993764658 hasConceptScore W1993764658C98274493 @default.